2004
DOI: 10.1086/381270
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Increased Burden of Illness Associated with Antimicrobial‐ResistantSalmonella entericaSerotype Typhimurium Infections

Abstract: This study investigated the burden of illness associated with 440 cases of Salmonella enterica serotype Typhimurium infection identified in Canada between December 1999 and November 2000. We categorized case subjects' infections by definitive phage type 104 (DT104) and antimicrobial-resistance patterns. These variables were then investigated as risk factors for hospitalization. Hospitalization was more likely to occur among case subjects whose infections were resistant to at least ampicillin, chloramphenicol a… Show more

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Cited by 132 publications
(79 citation statements)
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“…A second possibility propounded by other investigators is that antimicrobial drug-resistant Salmonella spp. is associated with increased virulence (21,22). We believe that the higher prevalence of ESC resistance in our ill children is of substantial public health importance and that the mechanisms leading to this increased resistance should be further investigated.…”
Section: Discussionmentioning
confidence: 94%
“…A second possibility propounded by other investigators is that antimicrobial drug-resistant Salmonella spp. is associated with increased virulence (21,22). We believe that the higher prevalence of ESC resistance in our ill children is of substantial public health importance and that the mechanisms leading to this increased resistance should be further investigated.…”
Section: Discussionmentioning
confidence: 94%
“…AMR is a major problem for the global health and economy [24]. In the developing countries, a high rate of infections usually coincides with a rapid development and spread of microbial resistance [25].…”
Section: Discussionmentioning
confidence: 99%
“…Antimicrobial resistance is a major problem for the global health and economy [8]. In the developing countries, a high rate of infections usually coincides with a rapid development and spread of microbial resistance [9].…”
Section: Discussionmentioning
confidence: 99%