Increased cariogenic biofilm formation on under-cured bulk fill composites

Melo, Mary Anne Sampaio de; Maktabi, Haifa; Ibrahim, Maria Salem; Balhaddad, Abdulrahman A.; Alkhubaizi, Qoot; Fugolin, Ana Paula Piovezan; Pfeifer, Carmem S.; Strassler, Howard E.

doi:10.1016/j.dental.2019.08.049

Cited by 1 publication

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“…Resin composite restorations are the most popular material used in dental practice because of their excellent esthetics and handling properties [ 86 , 87 ]. Resin composites are criticized for accumulating more plaque compared to other dental restorations such as amalgam and glass ionomer, which can release fluoride, zinc, silver, or copper as bioactive ingredients [ 88 , 89 ].…”

Section: Contact-killing Materials As a Strategy In Resin-based Rementioning

confidence: 99%

Emerging Contact-Killing Antibacterial Strategies for Developing Anti-Biofilm Dental Polymeric Restorative Materials

et al. 2020

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Polymeric materials are the first choice for restoring tooth cavities, bonding tooth-colored fillings, sealing root canal systems, and many other dental restorative applications. However, polymeric materials are highly susceptible to bacterial attachment and colonization, leading to dental diseases. Many approaches have been investigated to minimize the formation of biofilms over polymeric restorative materials and at the tooth/material interfaces. Among them, contact-killing compounds have shown promising results to inhibit dental biofilms. Contact-killing compounds can be immobilized within the polymer structure, delivering a long-lasting effect with no leaching or release, thus providing advantages compared to release-based materials. This review discusses cutting-edge research on the development of contact-killing compounds in dental restorative materials to target oral pathogens. Contact-killing compounds in resin composite restorations, dental adhesives, root canal sealers, denture-based materials, and crown cements have all demonstrated promising antibacterial properties. Contact-killing restorative materials have been found to effectively inhibit the growth and activities of several oral pathogens related to dental caries, periodontal diseases, endodontic, and fungal infections. Further laboratory optimization and clinical trials using translational models are needed to confirm the clinical applicability of this new generation of contact-killing dental restorative materials.

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Section: Contact-killing Materials As a Strategy In Resin-based Rementioning

confidence: 99%