Increased Expression Together with the Gene Regulation Network of NEIL3 Predicts Poor Prognosis and Correlates with Immune Infiltrates in Hepatocellular Carcinoma
Abstract:Background: Abnormal Nei endonuclease VIII-like 3 (NEIL3)expression is associated with carcinogenesis.
Methods: We used sequencing data from the Cancer Genome Atlas database, analyzed NEIL3 expression, gene regulation networks and the correlation with immune infiltrates in hepatocellular carcinoma (HCC). Clinicopathologic characteristics associated with overall survival in TCGA patients using Cox regression and the Kaplan-Meier method. Gene Set Enrichment Analysis was performed using TCGA data set. LinkedOmic… Show more
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