2021
DOI: 10.1007/s10620-021-06993-5
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Increased Fecal Bile Acid Excretion in a Significant Subset of Patients with Other Inflammatory Diarrheal Diseases

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Cited by 12 publications
(6 citation statements)
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“…Prior studies have shown a higher prevalence of IBS-like symptoms in CD than in UC. 2 Although the mechanism for this has not been determined, we speculate that comorbid conditions in CD, such as SIBO 22 and bile acid malabsorption, 23 as well as possibly fibrostenotic disease may increase risk for IBS-like symptoms in CD relative to UC.…”
Section: Discussionmentioning
confidence: 97%
“…Prior studies have shown a higher prevalence of IBS-like symptoms in CD than in UC. 2 Although the mechanism for this has not been determined, we speculate that comorbid conditions in CD, such as SIBO 22 and bile acid malabsorption, 23 as well as possibly fibrostenotic disease may increase risk for IBS-like symptoms in CD relative to UC.…”
Section: Discussionmentioning
confidence: 97%
“…Moreover, some studies used different criteria to diagnose BAM: in the two case reports the response to a trial of cholestyramine was considered diagnostic for BAM [ 18 , 21 ]. One study used both SeHCAT test and C4 plasma concentrations > 20 ng/mL [ 26 ]; two others used C4 serum levels [ 28 , 30 ]; one used total fecal bile acid and primary fecal bile acid levels [ 31 ].…”
Section: Bile Acid Diarrhea and Microscopic Colitis In The Current Li...mentioning
confidence: 99%
“…In almost all studies, patients with MC and BAM were treated with cholestyramine, with a percentage of responders ranging from 70 to 80% (just one study showed a lower efficacy [ 22 ]). Bajor et al [ 26 ] and Vijayvargiya et al [ 31 ] treated patients with budesonide, with clinical benefits. Furthermore, the case report of Rampton et al revealed an improvement in histologic findings of rectal biopsies after treatment with cholestyramine [ 18 ].…”
Section: Bile Acid Diarrhea and Microscopic Colitis In The Current Li...mentioning
confidence: 99%
“…d. Diverse intestinal inflammatory diseases in remission: A study of 47% of 51patients with celiac disease in remission, 53% of 34 patients with collagenous colitis in remission, and 50% of 32 with lymphocytic colitis in remission showed patients had increased fecal BA excretion 59 …”
Section: Introductionmentioning
confidence: 99%