Increased Frequency of Guillain-Barré Syndrome in HIV Infection: A Prospective Cohort Study

Bouic, Patrick

doi:10.4172/2155-6113.1000332

Cited by 2 publications

(2 citation statements)

References 29 publications

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“…The relationship between GBS and the stage of HIV infection is also unclear. The authors characterized the GBS as an indication of early HIV infection or seroconversion [186]. However, GBS has been reported in chronic HIV-1 infection cases or as a complication of immune reconstitution inflammatory syndrome in severely immunocompromised patients [187].…”

Section: Guillain-barré Syndrome (Gbs)mentioning

confidence: 99%

Viral infections and their relationship to neurological disorders

et al. 2021

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The chronic dysfunction of neuronal cells, both central and peripheral, a characteristic of neurological disorders, may be caused by irreversible damage and cell death. In 2016, more than 276 million cases of neurological disorders were reported worldwide. Moreover, neurological disorders are the second leading cause of death. Generally, the etiology of neurological diseases is not fully understood. Recent studies have related the onset of neurological disorders to viral infections, which may cause neurological symptoms or lead to immune responses that trigger these pathological signs. Currently, this relationship is mostly based on epidemiological data on infections and seroprevalence of patients who present with neurological disorders. The number of studies aiming to elucidate the mechanism of action by which viral infections may directly or indirectly contribute to the development of neurological disorders has been increasing over the years but these studies are still scarce. Comprehending the pathogenesis of these diseases and exploring novel theories may favor the development of new strategies for diagnosis and therapy in the future. Therefore, the objective of the present study was to review the main pieces of evidence for the relationship between viral infection and neurological disorders such as Alzheimer's disease, Parkinson's disease, Guillain-Barré syndrome, multiple sclerosis, and epilepsy. Viruses belonging to the families Herpesviridae, Orthomyxoviridae, Flaviviridae, and Retroviridae have been reported to be involved in one or more of these conditions. Also, neurological symptoms and the future impact of infection with SARS-CoV-2, a member of the family Coronaviridae that is responsible for the COVID-19 pandemic that started in late 2019, are reported and discussed.

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Section: Guillain-barré Syndrome (Gbs)mentioning

confidence: 99%

Viral infections and their relationship to neurological disorders

et al. 2021

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“…It could occur in any stage of HIV infection and is often the presenting indicator. Immune deregulation could be the cause for increased incidence of GBS in HIV-infected individuals and molecular mechanism of which permits further investigation [32]. HIV is more widespread in India which causes AIDS.…”

Section: Review Of Literaturementioning

confidence: 99%

A Review on Various Aspects of HIV Infection

Lingan¹

2018

HIV Curr Res

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Many people are affected by HIV infection worldwide, lack of ability of modern medication in developing an active vaccine against HIV is a global public health importance. Various aspects such as diseases associated with HIV infection, role of immune cells in diagnosis and treatment, significance of molecular changes during infection, complications in infants, impact of gender and social behaviour and diagnosis of disorders associated with HIV infection were discussed in this review. Affected patients would be associated with acute kidney injury, arterial stiffness, cardiovascular disease, Tuberculosis, intestinal parasite carriage and disruptive sleep apnea. Immune cells like CD4, CD8, CD38 T cells and natural killer cells have a vital role in diagnosis and treatment. DNA vaccines could play a major role to prevent or treat infectious diseases including HIV and would elicit T cell immunity, protective antibody responses and local mucosal immunity protective vaccine against HIV infection. Health professionals are responsible for diagnosis of disorders associated with HIV infection and follow-up of HIV-infected paediatric patients. There is a crucial need to improve and evaluate novel interventions that are tailored for this helpless population. Several factors such as income deficit, Pre-college residence, pornographic film viewing and believe in sexual abstinence for HIV prevention were found to be significant predictors of initiating premarital sex. Younger generations could be advised to maintain the virginity as cultural norm. Incorporation of socio-structural elements and geospatial techniques in analytical approaches would lead to better understanding of local dynamics and develop mediations that increase our facility of targeted HIV prevention services.

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Increased Frequency of Guillain-Barré Syndrome in HIV Infection: A Prospective Cohort Study

Cited by 2 publications

References 29 publications

Viral infections and their relationship to neurological disorders

Viral infections and their relationship to neurological disorders

A Review on Various Aspects of HIV Infection

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