Increased infection risk after hip hemiarthroplasty in institutionalized patients with proximal femur fracture

Gallardo-Calero, Irene; Larrainzar-Coghen, Thais; Rodríguez-Pardo, Dolors; Pigrau, Carles; Sánchez-Raya, Judith; Amat, Carles; Lung, Mayli; Carrera, Luis Gómez; Corona, Pablo S.

doi:10.1016/j.injury.2015.12.032

Cited by 26 publications

(30 citation statements)

References 28 publications

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“…Only 4 patients with ASB had an early-PJI which represents an incidence of 2.7%. Although this is lower than expected [4,7,8], it is consistent with the latest data collected in the VINCat registry (surveillance database of nosocomial infections in Catalonia) [5]. When investigating risk factors for early-PJI our study focuses on preoperative ASB.…”

Section: Discussionsupporting

confidence: 79%

“…Published studies show that it leads to a reduction in the rate of PJIs in HHA with no associated increase in complications [25][26][27]. This approach could justify a global reduction of early-PJ rates compared to our previous incidence between 2011 and 2013 [4].…”

Section: Discussionmentioning

confidence: 89%

“…Early-periprosthetic joint infection (early-PJI) after joint replacement is a challenging complication. Rates of early-PJI are higher in HHA patients than in total hip arthroplasty (THA) and range between 1.3-9% [1][2][3][4][5].…”

Section: Introductionmentioning

confidence: 99%

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Role of asymptomatic bacteriuria on early periprosthetic joint infection after hip hemiarthroplasty. BARIFER randomized clinical trial

Rodríguez-Pardo

Toro

Guío-Carrión

et al. 2021

Eur J Clin Microbiol Infect Dis

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Purpose: To evaluate preoperative asymptomatic bacteriuria (ASB) treatment on the reduction of earlyperiprosthetic joint infections (early-PJIs) after hip hemiarthroplasty (HHA) for fracture.Methods: Open-label, multicentre RCT comparing 3gr of fosfomycin-trometamol with non-treatment. A parallel follow-up cohort without ASB was established. Primary outcome: early-PJI within 3 months after HHA.Results: patients enrolled (mean age 84.3years); 152(25%) with ASB (77 treated with fosfomycin and 75 controls) and 442(75%) without. ASB was not a predictor of early-PJI (OR:1.06[95%CI:0.33-3.38], p=0,9228) and its treatment did not modify early-PJI incidence (OR

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Section: Discussionsupporting

confidence: 79%

Section: Discussionmentioning

confidence: 89%

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Role of asymptomatic bacteriuria on early periprosthetic joint infection after hip hemiarthroplasty. BARIFER randomized clinical trial

Rodríguez-Pardo

Toro

Guío-Carrión

et al. 2021

Eur J Clin Microbiol Infect Dis

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“…To our knowledge, there are limited studies describing a large cohort of patients with a PJI. Our incidence rates of PJI after hip fracture surgery (1.6%) and after primary THR (0.9%) are relatively low compared to other literature and national surveillance data (2-17% vs 1% respectively) 1 , 7 , 11 , 13 , 14 , 19 . Since the incidence rates of PJI are very low, it is important to follow-up these patients to evaluate their functional well-being and eventually establish evidence-based treatment protocols.…”

Section: Discussioncontrasting

confidence: 54%

Prosthesis retention after an infected hip prosthesis: hip fractures versus primary total hip prosthesis, data from 1998 - 2015

Neve

Steens

2018

J. Bone Joint Infect.

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Background: A prosthetic joint infection (PJI) is a serious complication and specifically a burden for patients after hip fracture surgery, as they are mostly frail elderly patients with multiple comorbidities. Since treatment protocols are lacking there is a need to evaluate current practice.Aim: To evaluate the difference in prosthesis retention after an infected primary total hip replacement (THR) compared to PJI after hip prosthesis surgery performed for a hip fracture.Methods: We retrospectively collected data of patients who developed PJI after primary THR or after hip fracture surgery (THR or hemiarthroplasty) in the Westfriesgasthuis Hospital between 1998 and 2015. Main outcome variables were DAIR treatment and prosthesis retention.Findings: A PJI developed in 48 patients after primary THR and in 23 patients after hip fracture surgery. DAIR was performed in all patients after primary THR and in 87.0% of patients after hip fracture surgery (p<0.05). In 11.4% of patients after primary THR, revision surgery was performed within 1 year after PJI compared to 34.8% after hip fracture surgery (p<0.05). Only 2.1% of patients deceased within 1 year after infection of primary THR compared to 34.8% after hip fracture surgery (p<0.05).Conclusion: Our results showed that prosthesis retention in patients with a PJI after hip fracture surgery is 23% lower than in patients with a PJI after primary THR. This is probably due to the fact that patients who experience a hip fracture are mostly frail elderly with multiple comorbidities and therefore less able to conquer a PJI.

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“…mit Prothesen-und Implantatinfektionen nach PFF versterben innerhalb eines Jahres [20]. Zunehmende Antibiotikaresistenzen führen dazu, die Leitlinien zur intraoperativen antibiotischen Infektionsprophylaxe zu überdenken [20,21]. Ohne Zweifel sollte dabei das Risikomanagement in der elektiven Endoprothetik auch auf die geriatrischen Pat.…”

Section: Ausblick Für Die Zukunftunclassified

Response to the Letter to the Editor: Sitte-Zöllner A, Walcher F, Geginat G, Piatek S. Z Orthop Unfall 2017; 155: 344 – 345. doi:10.1055/s-0043-103015

et al. 2017

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Increased infection risk after hip hemiarthroplasty in institutionalized patients with proximal femur fracture

Cited by 26 publications

References 28 publications

Role of asymptomatic bacteriuria on early periprosthetic joint infection after hip hemiarthroplasty. BARIFER randomized clinical trial

Role of asymptomatic bacteriuria on early periprosthetic joint infection after hip hemiarthroplasty. BARIFER randomized clinical trial

Prosthesis retention after an infected hip prosthesis: hip fractures versus primary total hip prosthesis, data from 1998 - 2015

Response to the Letter to the Editor: Sitte-Zöllner A, Walcher F, Geginat G, Piatek S. Z Orthop Unfall 2017; 155: 344 – 345. doi:10.1055/s-0043-103015

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