Increased Iodine Uptake in the Nabothian Cyst

Liu, Shuai; Zhang, Min; Qu, Yumin; Pan, Yu; Zhang, Yifan

doi:10.1097/rlu.0b013e31827a0037

Cited by 7 publications

(1 citation statement)

References 11 publications

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“…We have previously reported a case of increased iodine uptake in cervical nabothian cysts 2. Since then, our attention has focused on 131 I-WBS after 131 I therapy in our department; this has indicated that the rate of increased focal iodine activity in the middle of the lower abdomen of patients with DTC is higher than that considered previously.…”

Section: Introductionmentioning

confidence: 86%

Nabothian cyst associated with high false-positive incidence of iodine-131 uptake in whole-body scans after treatment for differentiated thyroid cancer

Liu

Zhang

Pan

et al. 2013

Nuclear Medicine Communications

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ObjectiveThis study aimed to analyze the focal uptake of iodine-131 (131I) in the upper pelvis superior to the urinary bladder on whole-body images of patients who underwent this treatment after thyroidectomy for differentiated thyroid cancer.MethodsBetween June 2012 and March 2013, 205 patients (72 men and 133 women, with an average age of 47.9±11.7 years) who underwent 131I radioactive treatment after thyroid cancer surgery were analyzed retrospectively. Pathological findings confirmed papillary thyroid carcinoma. A whole-body scan was acquired 5 days after 100–120 mCi sodium iodide was administered orally to the patients. Single-photon emission computed tomography/computed tomography (SPECT/CT) scanning was carried out to locate the lesion; this showed abnormal intense activity in the upper pelvis superior to the urinary bladder, which was further evaluated by ultrasonography.ResultsUsing 131I-SPECT scanning, five (3.76%) female patients were shown to have abnormal focal radioactivity in the lower abdomen. Subsequent SPECT/CT examination showed that the radioactivity was located in the cervix in four of the five patients and in the sigmoid colon in one patient. Transvaginal ultrasonography was performed in the former four patients, which revealed several echo-free regions in the cervix. These findings are consistent with the diagnosis of a nabothian cyst. Three of these patients were administered a second course of radioiodine therapy. Radioactive uptake was still visible at the same sites on whole-body imaging.ConclusionNabothian cyst should be considered in cases in which abnormal uptake in the upper pelvis superior to the urinary bladder is detected on 131I whole-body scans after differentiated thyroid cancer resection.

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Section: Introductionmentioning

confidence: 86%

Nabothian cyst associated with high false-positive incidence of iodine-131 uptake in whole-body scans after treatment for differentiated thyroid cancer

Liu

Zhang

Pan

et al. 2013

Nuclear Medicine Communications

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Increased 131I Accumulation in the Polyacrylamide Hydrophilic Gel Used for Breast Augmentation

Zhang

et al. 2014

Clinical Nuclear Medicine

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A 37-year-old woman with papillary thyroid cancer received repeat 131I therapy. The first posttherapy scan revealed only activity in the neck. However, both the second and third posttherapy scans showed intense activity in the anterior lower chest bilaterally, suggestive of breast uptake. However, the SPECT/CT images demonstrated that the iodine activity was not located in the breast tissue. Instead, the activity was inside the polyacrylamide hydrophilic gels she received 10 years ago for breast augmentation.

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