Background
Visual information about subclinical atherosclerosis was provided to physicians and participants in the VIPVIZA trial, inclusion 2013 to 2016 in northern Sweden, aiming to improve adherence to cardiovascular disease (CVD) prevention guidelines. Pictorial risk information may be more actionable.
Aim
Investigate the effect of intervention with pictorial risk information on time to first dispensing of statins.
Method
Asymptomatic atherosclerotic disease was screened for by carotid ultrasound examination in 3532 participants enrolled in VIPVIZA, of those 3000 met the criteria for this study. Participants were randomly assigned to receive pictorial risk information consisting of graphical representation of atherosclerosis as compared to a control group without intervention. Time to initiation of statins was assessed during a five-year follow-up through the National prescribed drug register. After three years, both groups were re-examined and received the intervention information.
Results
In the intervention group, initiation of statins increased considerably for the first three years and a smaller increase was also seen after re-intervention. After the cross-over, the control group showed a sharp increase in initiation of statins, almost reaching the same proportion treated at 5 years. The propensity to initiate statin treatment increased over the study period and there was no difference between men and women.
Conclusions
The pictorial information had an effect on time to initiation of statins, both as original and repeated intervention and also in the control group after single arm cross-over. The current study supports pictorial information as a tool to shorten time to initiation of statins for CVD prevention.
The VIPVIZA study is registered with ClinicalTrials.gov, number NCT01849575.