Increased Levels of IL-17, IL-23, MIP-1α, MCP-1 and Global Leukocytes in Fibromyalgia Patients

Pernambuco, Andrei Pereira; Fonseca, Angélica Cristina; Oliveira, Gabriella Luciana de; Faria, Priscila Conceição; Silva, Raimisson Vieira; Meireles, Cecília; Arantes, Saulo Elyas; Silva, Fernanda Cristina; Reis, Débora d’Ávila

doi:10.1080/24708593.2017.1357664

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“…Multiple studies have reported alterations in several immune cell types in FMS in addition to nervous system contribution. 5,8,[42][43][44]60,61,69,71 Although several mechanisms for the immunopathology of FMS have been proposed, no consensus has been reached. A recent meta-analysis showed upregulated immune-inflammatory and compensatory immuneregulatory systems in FMS, but the precise involvement of the immune system in the pathophysiology of FMS is unclear.…”

Section: Discussionmentioning

confidence: 99%