Increased odds ratio for COVID‐19 in patients with recurrent aphthous stomatitis

Katz, Joseph; Yue, Sijia

doi:10.1111/jop.13114

Cited by 28 publications

(45 citation statements)

References 11 publications

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“…One study only reported recurrent aphthous stomatitis in COVID-19 patients, and one study reported oral changes but failed to describe the type of changes noted. 10 , 11 …”

Section: Resultsmentioning

confidence: 99%

“…There was only one study in this review where there was a comparator group: patients with recurrent aphthous ulceration and COVID-19 as compared to patients with COVID-19 without recurrent aphthous ulceration. 11 This study only focused on recurrent aphthous ulceration, which limits its scope in determining the causal link to various other types of lesions. Nevertheless, they stated a strong association between COVID-19 and recurrent aphthous stomatitis.…”

Section: Discussionmentioning

confidence: 99%

“…Nevertheless, they stated a strong association between COVID-19 and recurrent aphthous stomatitis. 11 …”

Section: Discussionmentioning

confidence: 99%

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Oral mucosal lesions in patients with COVID-19: a systematic review

Bhujel

Zaheer

Singh

2021

British Journal of Oral and Maxillofacial Surgery

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COVID-19 is a new disease which mainly presents with respiratory symptoms, however can present with a multitude of signs and symptoms affecting various body systems. Several oral manifestations related to COVID-19 have also been reported. We carried out a systematic review to explore the types of oral mucosal lesions that have been reported in COVID-19 related literature up to the date of 25th of March 2021. A structured electronic databases search using Medline, Embase and CINAHL as well as gray literature search using Google Scholar revealed a total of 322 studies. After removal of duplicates and the primary and secondary filtering process, 12 studies were included for final appraisal. We have identified several different types of oral mucosal lesions in patients with COVID-19 infection, present at various locations within the oral cavity. Most of the studies appraised in this review were of high risk of bias according to the Joanna Briggs Institute checklist. The current published literature does not allow differentiation as to whether the oral lesions are caused by the viral infection itself or instead related to oral manifestations secondary to existing patient comorbidities or treatment instigated to combat the disease. It is important for healthcare professionals to be aware of the possible link between COVID-19 and oral mucosal lesions, and we hereby discuss our findings.

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“…One study only reported recurrent aphthous stomatitis in COVID-19 patients, and one study reported oral changes but failed to describe the type of changes noted. 10 , 11 …”

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Oral mucosal lesions in patients with COVID-19: a systematic review

Bhujel

Zaheer

Singh

2021

British Journal of Oral and Maxillofacial Surgery

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“…According to Santos et al (2020) e Ansari et al (2020) even healthy patients who are affected by Covid-19 may present these oral manifestations, but pointing out hypotheses whether it is a result of strong direct viral infection or decreased immune response capacity of the patient that could open the door to opportunistic infections and also to pharmacological treatments performed. According to Katz and Yue (2021) there is higher prevalence of recurrent aphthous stomatitis in patients confirmed with Covid-19 than in healthy patients. Xu et al (2020) point to the oral cavity as a target for novel coronavirus, explained by the wide distribution of receptors in the oral tissues and the spectrum of changes published in the literature associated with Covid-19 including aphthous and vesicular ulcerations (Xu et al, 2020).…”

Section: Discussionmentioning

confidence: 99%

Manifestações orais em pacientes infectados com sars COV-2 / Oral manifestations from sars COV-2 in infected patients

Stroparo¹,

Lyra²,

Abuabara³

et al. 2021

BJDV

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The recent outbreak of the novel coronavirus 2019 (Covid-19) spread rapidly throughout several countries around the worldand has posed enormous health challenges. Symptom of Covid-19 are non-specific and the disease presentation can range from no symptoms (asymptomatic) to severe pneumonia and death. The most commonly reported oral manifestations in the literature are ulcer, erosion, bulla, vesicle, pustule, fissured or depapillated tongue, macule, papule, plaque, pigmentation, halitosis, among others. The professionals must be prepared to recognize theoral manifestations of the disease to promote the most adequate treatment. This study presents 5 cases of oral manifestations in patients diagnosed with Covid-19. The patients presented ulcerations, vesiculopapular lesions, papillary lesions, lingual erythesa, keratose-like lesions and white plaque. Lips, tongue, labial mucosa, palate and gum were affected. If this hypothesis is proven, when health professionals observe these oral manifestations, they could refer these patients to be tested and perform the appropriate treatment.

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“…On reviewing the currently growing evidence on aphthous stomatitis of COVID-19 patients, we have found 22 cases reported in 8 publications (7 case reports, 1 prevalence study). [5][6][7][8][9][10][11][12] Fourteen cases (63.6%) were from Americas, five (22.7%) from Europe, two (9%) from the Middle East, and one (4.5%) from Asia-Pacific ( Table 2). The aphthous lesions were equally distributed across gender; however, female predominance was noticed in the prevalence study of Florida, which is similar to our series.…”

Section: Sars-cov-2) and Aphthousmentioning

confidence: 99%