Increased Prevalence of Gastroesophageal Reflux Symptoms in Patients With COPD

Oropharyngeal dysphagia in patients with chronic obstructive pulmonary disease: a systematic review

“…It was apparent that not all studies could be easily classifi ed using the numerical scale due to overlap in design criteria. Therefore, letter grades (Column 1, ; 6 were Level C [36][37][38][39][40][41] ; and 6 were Level D 16,[47][48][49][50][51] . Seven of the 47 articles investigated the relationship between COPD and oropharyngeal dysphagia 8,[11][12][13][14][15][16] .…”

Extrapulmonary comorbidities in chronic obstructive pulmonary disease: state of the art

“…Although symptoms of gastroesophageal reflux disease (GERD) occur in up to 30-60% of COPD patients [15,87] and are associated with more severe disease, many episodes of reflux are asymptomatic and are only detected by esophageal manometry. The relative risk of patients accruing a diagnosis of GERD is 1.46 in the year following COPD diagnosis [88].…”

Gastroesophageal Reflux Symptoms in Patients with Chronic Obstructive Pulmonary Disease

“…suggest a possible correlation between COPD severity and more frequent symptoms of GER [5]. Some authors found an increased prevalence of GER symptoms in patients with COPD [9].…”

“…Gastroesophagal reflux disease (GERD) is the collective term used to describe abnormal reflux of gastric content into the esophagus as well as the symptoms and mucosal disease associated with it clinical manifestations of GERD include heartburn, regurgitation, dysphagia, chest pain, cough and other esophageal symptoms [4,5].…”

“…In contrast to asthma, the relationship between GER and chronic obstructive pulmonary disease (COPD) is not well established in previous years, but in last decade there are more studies that investigate the relation between GER and COPD. http://www.mjms.mk/ http://www.id-press.eu/mjms Two explanations have been proposed: Reflux induces microaspiration of gastric contents that irritate airways or symptoms may be induced without direct exposure of the airways to refluxant material; acid reflux into distal esophagus induces vagally mediated reflex bronchoconstriction [1][2][3]5].…”