Increased Pulmonary-Systemic Pulse Pressure Ratio Is Associated With Increased Mortality in Group 1 Pulmonary Hypertension

Ruth, Benjamin; Bilchick, Kenneth C.; Mysore, Manu; Mwansa, Hunter; Harding, William C.; Kwon, Younghoon; Kennedy, Jamie L.W.; Mazurek, Jeremy A.; Mihalek, Andrew; Smith, Larissa L.; Mejia-Lopez, Eliany; Parker, Alex M.; Welch, Timothy; Mazimba, Sula

doi:10.1016/j.hlc.2018.05.199

Cited by 4 publications

(2 citation statements)

References 31 publications

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“…The pulmonary-systemic pulse pressure ratio, a marker of biventricular efficiency, will increase during adverse ventricular independence and decrease with successful interventions. 86 As a simpler alternative, the mPAP/MAP (mean arterial pressure) ratio can be monitored.…”

Section: Pulmonary Hypertensionmentioning

confidence: 99%

Risk Factors for Mitral Valve Surgery: Atrial Fibrillation and Pulmonary Hypertension

Lombard

Liang

2019

Semin Cardiothorac Vasc Anesth

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Section: Pulmonary Hypertensionmentioning

confidence: 99%

Risk Factors for Mitral Valve Surgery: Atrial Fibrillation and Pulmonary Hypertension

Lombard

Liang

2019

Semin Cardiothorac Vasc Anesth

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“…Hemodynamic parameters, such as pulmonary arterial pulse pressure [7] or the pulmonary-systemic pulse pressure ratio [8], had a prognostic impact on patient outcomes; nonetheless, none of these parameters have been validated in Taiwanese patients. Therefore, we aimed to compare the clinical features and survival of patients with CTD-PAH and iPAH from a tertiary referral center and determine potential risk factors for PAH mortality.…”

Section: Introductionmentioning

confidence: 99%

Connective Tissue Disease-Associated Pulmonary Arterial Hypertension in Southern Taiwan: A Single-Center 10-Year Longitudinal Observation Cohort

Lin

Hsu

et al. 2021

Healthcare

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Background: Pulmonary arterial hypertension (PAH) is a life-threatening disease with different etiologies and outcomes. We aimed to explore differences in clinical features and outcomes of idiopathic PAH (iPAH) and connective tissue disease-related PAH (CTD-PAH) in Taiwanese patients and determine risk factors for mortality. Methods: We retrospectively reviewed the medical records of patients with right-sided heart catheterization-diagnosed PAH between January 2005 and December 2015. The iPAH (n = 31) and CTD-PAH (n = 14) patients were enrolled and followed until December 31, 2019. Between-group comparisons were conducted. Potential predictors of the mortality of PAH were determined using the Cox proportional hazard regression model. Results: CTD-PAH patients had higher levels of N-terminal pro-brain natriuretic peptide (NT-proBNP) and lower predicted diffusing capacity of carbon monoxide (DLCO) than iPAH patients. The mortality rates were similar between CTD-PAH and iPAH (21.4% vs. 22.6%, p = 0.99). A mean pulmonary arterial pressure (mPAP) > 46 mmHg was a predictor of PAH-induced mortality (adjusted hazard ratio 21.8, 95% confidence interval 2.32–204.8). Conclusions: A higher mPAP level, but not underlying CTDs, imposed a significantly increased risk of mortality to patients with PAH.

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Hemodynamic and Echocardiographic Characteristics and the Presence of Pulmonary Hypertension in Patent Ductus Arteriosus Patients who Underwent Transcatheter Closure

Yeh²,

Lee

et al. 2023

Pediatr Cardiol

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Increased Pulmonary-Systemic Pulse Pressure Ratio Is Associated With Increased Mortality in Group 1 Pulmonary Hypertension

Cited by 4 publications

References 31 publications

Risk Factors for Mitral Valve Surgery: Atrial Fibrillation and Pulmonary Hypertension

Risk Factors for Mitral Valve Surgery: Atrial Fibrillation and Pulmonary Hypertension

Connective Tissue Disease-Associated Pulmonary Arterial Hypertension in Southern Taiwan: A Single-Center 10-Year Longitudinal Observation Cohort

Hemodynamic and Echocardiographic Characteristics and the Presence of Pulmonary Hypertension in Patent Ductus Arteriosus Patients who Underwent Transcatheter Closure

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