Increased response of diastolic blood pressure to exercise in patients with coronary artery disease: an index of latent ventricular dysfunction?

Abstract

In patients with coronary artery disease an abnormal increase in diastolic blood pressure during exercise stress testing correlated well with left ventricular systolic function at rest but not with the number of obstructed coronary arteries. The abnormal response of diastolic blood pressure probably reflects deterioration of myocardial function.

The effect of different doses of aerobic exercise training on exercise blood pressure in overweight and obese postmenopausal women

“…However, in our study and other previous reports in populations with elevated blood pressure 9, 12 a mean increase in DBP has been observed at sub-maximal intensities. Whether this increase in DBP is a hallmark of individuals with hypertension is beyond the scope of this paper, however it may warrant further study, as an increase in DBP with exercise has been associated with cardiovascular abnormalities in individuals with coronary artery disease 21, 22 .…”

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“…There was a remarkable elevation of the diastolic BP (160/135 mmHg), consistent with ischemic left ventricular dysfunction since, in comparison with a resting diastolic BP of 110/85 a month before lift-off with no resting BP available before the stress test, there was a 50 mm difference; far above the cut-off abnormal level of > 15 mmHg ---with 100% specificity. This abnormal response of the diastolic BP probably reflects a deterioration of myocardial function [1][2][3][4]. At age 39, Armstrong may have had in addition coronary artery disease, but not coming to light until his first myocardial infarction at age 61.…”