Increased risk of COVID-19-related admissions in patients with active
                        solid organ cancer in the West Midlands region of the UK: a retrospective
                        cohort study

Akingboye, Akinfemi; Mahmood, Fahad; Amiruddin, Nabeel; Reay, Michael; Ogunwobi, Olorunseun O.

doi:10.1136/bmjopen-2021-053352

Cited by 2 publications

(1 citation statement)

References 36 publications

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“…As SARS-CoV-2 started spreading in the late 2019 and early 2020, it became clear that individuals particularly at risk of severe consequences of COVID-19 are older people and those with long-term cardiovascular [ 7 , 8 ] and pulmonary conditions [ 9 ] as well as those with generally weakened immune responses [ 10 ], in particular those suffering from cancer [ 11 ]. The ability of the virus to transmit through air via droplets and in aerosols makes infections more probable in contexts in which many people are gathered in small unventilated spaces.…”

Section: Introductionmentioning

confidence: 99%

Deaths during the first year of the COVID-19 pandemic: insights from regional patterns in Germany and Poland

et al. 2023

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Background Given the nature of the spread of SARS-CoV-2, strong regional patterns in the fatal consequences of the COVID-19 pandemic related to local characteristics such as population and health care infrastructures were to be expected. In this paper we conduct a detailed examination of the spatial correlation of deaths in the first year of the pandemic in two neighbouring countries – Germany and Poland, which, among high income countries, seem particularly different in terms of the death toll associated with the COVID-19 pandemic. The analysis aims to yield evidence that spatial patterns of mortality can provide important clues as to the reasons behind significant differences in the consequences of the COVID-19 pandemic in these two countries. Methods Based on official health and population statistics on the level of counties, we explore the spatial nature of mortality in 2020 in the two countries – which, as we show, reflects important contextual differences. We investigate three different measures of deaths: the officially recorded COVID-19 deaths, the total values of excessive deaths and the difference between the two. We link them to important pre-pandemic regional characteristics such as population, health care and economic conditions in multivariate spatial autoregressive models. From the point of view of pandemic related fatalities we stress the distinction between direct and indirect consequences of COVID-19, separating the latter further into two types, the spatial nature of which is likely to differ. Results The COVID-19 pandemic led to much more excess deaths in Poland than in Germany. Detailed spatial analysis of deaths at the regional level shows a consistent pattern of deaths officially registered as related to COVID-19. For excess deaths, however, we find strong spatial correlation in Germany but little such evidence in Poland. Conclusions In contrast to Germany, for Poland we do not observe the expected spatial pattern of total excess deaths and the excess deaths over and above the official COVID-19 deaths. This difference cannot be explained by pre-pandemic regional factors such as economic and population structures or by healthcare infrastructure. The findings point to the need for alternative explanations related to the Polish policy reaction to the pandemic and failures in the areas of healthcare and public health, which resulted in a massive loss of life.

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Section: Introductionmentioning

confidence: 99%

Deaths during the first year of the COVID-19 pandemic: insights from regional patterns in Germany and Poland

et al. 2023

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COVID-19 perceptions, impacts, and experiences: a cross-sectional analysis among New Jersey cancer survivors

et al. 2022

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Background Cancer survivors are particularly vulnerable to adverse COVID-19-related outcomes, but limited data exist on perceptions about the pandemic and related experiences in this group. Methods In a cross-sectional analysis of 494 survivors of genitourinary, breast, gynecologic, colorectal, lung, melanoma, or thyroid cancer, from a larger study of cancer survivors in New Jersey, we assessed perceptions about COVID-19 threat, impacts, and experiences using three validated instruments. Responses were coded on a 7-point Likert scale, and subscales were averaged across included items, with higher scores indicating greater perceptions of COVID-19 threat and greater impacts and experiences because of the pandemic. Multivariable linear regression models were used to determine factors associated with higher scores, with Bonferroni correction for multiple comparisons. Results In general, cancer survivors reported moderate perceived COVID-19 threat (3 items, mean score = 3.71 ± 1.97), minimal COVID-19-related impacts (6 items, mean score = 2.23 ± 1.34), and COVID-19-related experiences (7 items, mean score = 2.17 ± 1.00). COVID-19 impact subscale scores varied little (mean subscale score range = 2.09 to 2.29), while COVID-19 experiences subscale scores were quite variable (mean subscale score range = 1.52 to 3.39). Asian American/Pacific Islander race, Black race, female sex, and having more cardiovascular and metabolic and other comorbidities were associated with higher scores on the perceived coronavirus threat questionnaire. Having completed the COVID-19 questionnaires earlier in the pandemic, younger age, American/Pacific Islander race, Hispanic ethnicity, and having more comorbidities were associated with higher scores on the COVID-19 impact questionnaire. Younger age, racial minority status, and having more cardiovascular and metabolic comorbidities were associated with higher scores on the COVID-19 experience questionnaire. Conclusion Among cancer survivors in New Jersey-a state that experienced high rates of COVID-19 infection-sociodemographic and health-related factors (e.g., race and ethnicity, sex, and multimorbidity) correlate with greater perceptions of COVID-19 threat, impacts, and experiences. Implications for Cancer Survivors Studies are needed to examine the influence of vaccination status on COVID-19 perceptions and identify inequities in clinical outcomes due to pandemic-related disruptions to cancer care.

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Increased risk of COVID-19-related admissions in patients with active solid organ cancer in the West Midlands region of the UK: a retrospective cohort study

Cited by 2 publications

References 36 publications

Deaths during the first year of the COVID-19 pandemic: insights from regional patterns in Germany and Poland

Deaths during the first year of the COVID-19 pandemic: insights from regional patterns in Germany and Poland

COVID-19 perceptions, impacts, and experiences: a cross-sectional analysis among New Jersey cancer survivors

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