Increased risk of glomerulonephritis and chronic kidney disease in relation to the severity of psoriasis, concomitant medication, and comorbidity: a nationwide population-based cohort study

Abstract

Psoriasis was associated with a higher risk of developing CKD and GN. High severity, psoriatic arthritis involvement and concomitant NSAIDs use further increased the risk of CKD in patients with psoriasis.

Increased risk of arrhythmia in patients with psoriatic disease: A nationwide population-based matched cohort study

“…However, the reliability and validity of using these methods for grouping severe psoriasis and PSA has been demonstrated in previous studies and verified through sensitivity analyses. 3,4,47 Nevertheless, systemic treatment, rather than severe psoriasis itself may affect the outcomes. Systemic antipsoriatic treatment in patients with psoriasis may reduce cardiovascular events.…”

“…1,2 Psoriasis has been associated with increased prevalence of cardiovascular risk factors, including hypertension, diabetes mellitus, and dyslipidemia. [3][4][5] Recent studies also indicate that patients with severe psoriasis have higher mortality, mainly because of higher risk of cardiovascular death (hazard ratio [HR] 1.57; 95% confidence interval [CI] 1. 26-1.96).…”

Response to ‘Kidney disease in moderate-to-severe psoriasis: a critical appraisal’

“…In the time since our study was published, a few other papers have also reported an increased risk of CKD and ESRD among patients with severe psoriasis, 6,7 and an increased risk of death from renal disease among patients with psoriasis. 8 …”

Increased risk of psoriasis following scabies infection: A nationwide population‐based matched‐cohort study

“…Psoriasis has been found to be associated with diabetes, metabolic syndromes, CKD, cardiovascular disease and COPD in previous studies . Immune‐mediated processes are believed to play a role in these associations.…”