Increased Risk of Peripheral Arterial Disease in Patients With Abdominal Aortic Aneurysm: A Retrospective Cohort Study (Version 5)

Lin, Yi-Ting; Chen, Hsuan-Ju; Chen, Pei–Chun; Sung, Fung‐Chang

doi:10.1177/0003319718757615

Cited by 5 publications

(7 citation statements)

References 38 publications

(57 reference statements)

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“…Besides the association between AAAs and PAD reported by Lin et al, 1 there is a strong association between AAAs and several other diseases, both CVD and non-CVD, such as cancer, periodontitis, CKD, SLE, COPD, and organ transplantation. It is important for physicians to be aware of these associations so that they have a higher index of suspicion for the early detection and timely management of AAAs in patients with these conditions.…”

Section: Discussionmentioning

confidence: 74%

“…Abdominal aortic aneurysms share the same vascular risk factors with these diseases (eg, smoking, hyperlipidemia, and hypertension). 5,6 Furthermore, atherosclerosis is a systemic disease, and the concomitant manifestation of arterial disease in >1 arterial bed is not unusual 5,6 ; the study by Lin et al 1 confirms this association.…”

Section: Abdominal Aortic Aneurysms and Vascular Disease In Other Artmentioning

confidence: 85%

“…33 In the study by Lin et al, a strong association is reported between DM with the development of AAAs (adjusted HR = 6.89; 95% CI = 1.43-33.3; P < .05). 1 This may be explained by the high prevalence of other vascular risk factors in the patient cohort that counterbalanced any protective effect of DM. Their finding also suggests that the association between AAAs and PAD is quite strong because it “overcomes” the effect of DM.…”

Section: Abdominal Aortic Aneurysms and Dmmentioning

confidence: 99%

“…In this issue of Angiology , Lin et al evaluated the risk of peripheral arterial disease (PAD) in patients with abdominal aortic aneurysm (AAA). 1 They compared the incidence of PAD in a cohort of 6590 patients with AAA versus 6590 controls without AAA. They showed that the incidence of PAD was >3.5-fold greater in the AAA compared with the non-AAA cohort (14.1 vs 3.66/1000 person-years; crude hazard ratio [HR] = 3.70; 95% confidence interval [CI] = 3.00-4.55; adjusted HR = 3.56; 95% CI = 2.89-4.39).…”

mentioning

confidence: 99%

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The Association Between Abdominal Aortic Aneurysms With Cardiovascular and Noncardiovascular Diseases

2018

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Section: Discussionmentioning

confidence: 74%

Section: Abdominal Aortic Aneurysms and Vascular Disease In Other Artmentioning

confidence: 85%

Section: Abdominal Aortic Aneurysms and Dmmentioning

confidence: 99%

mentioning

confidence: 99%

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The Association Between Abdominal Aortic Aneurysms With Cardiovascular and Noncardiovascular Diseases

2018

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“… 52 Lin et al recently published data on 6590 people with AAA, and found an increased risk of developing PAD in this cohort. 53 …”

Section: Discussionmentioning

confidence: 99%

Screening for Abdominal Aortic Aneurysms and Risk Factors in 65-Year-Old Men in Oslo, Norway

Rabben

Mansoor

Bay

et al. 2021

VHRM

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Purpose To investigate the prevalence of and risk factors for abdominal aortic aneurysm (AAA) in 65-year-old men in Oslo, Norway. Materials and Methods From May 2011, until September 2019, the annual population of 65-year-old men living in Oslo were invited to an ultrasonographic screening of the abdominal aorta. Candidates received a one-time invitation by mail, including a questionnaire on possible risk factors and comorbidities. Abdominal aortic outer-to-outer diameter and ankle-brachial index were measured by the screening team. Participants were allocated into three groups: non-, sub- and aneurysmal aorta. Written information on recommended follow-up regime was given to participants with an aortic diameter ≥25 mm. Univariate and multivariate analyses of potential risk factors were performed, in addition to descriptive analyses and significance testing. Results In total, 19,328 were invited, 13,215 men were screened, of which 12,822 accepted inclusion in the study. Aortic diameter was registered for 12,810 participants and 330 men had aortic diameter ≥30 mm, giving a prevalence of AAA of 2.6% (95% confidence interval (CI) 2.31–2.86). We identified 4 independent risk factors for AAA: smoking (OR = 3.64, 95% CI 2.90–4.58), hypertension (OR = 1.87, 95% CI 1.49–2.35), BMI >30 (OR = 1.02, 95% CI 1.00–1.03), and diabetes mellitus (OR = 0.52, 95% CI 0.35–0.79), the latter showing an inverse association with AAA growth. A subgroup of 862 men with aortic diameters 25–29 mm had a significantly higher prevalence of BMI >25, smoking and family history of AAA, compared to participants with aortic diameter <25 mm. Conclusion Among the participants in this study, the prevalence of abdominal aortic aneurysms was 2.6%. Participants with AAA more frequently reported cardiovascular risk factors, and less frequently diabetes mellitus.

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Current Imaging Strategies in Patients with Abdominal Aortic Aneurysms

Ristow,

Riedel,

Lenz

et al. 2023

Rofo

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Background An abdominal aortic aneurysm (AAA) is defined as a localized dilatation of the abdominal aorta of ≥ 3 cm. With a prevalence of 4–8 %, AAA is one of the most common vascular diseases in Western society. Radiological imaging is an elementary component in the diagnosis, monitoring, and treatment planning of AAA patients. Method This is a narrative review article on preoperative imaging strategies of AAA, incorporating expert opinions based on the current literature and standard-of-care practices from our own center. Examples are provided to illustrate clinical cases from our institution. Results and Conclusion Radiological imaging plays a pivotal role in the initial diagnosis and monitoring of patients with AAA. Ultrasound is the mainstay imaging modality for AAA screening and surveillance. Contrast-enhanced CT angiography is currently considered the gold standard for preoperative imaging and image-based treatment planning in AAA repair. New non-contrast MR angiography techniques are robustly applicable and allow precise determination of aortic diameters, which is of critical importance, particularly with regard to current diameter-based surgical treatment guidelines. 3D imaging with multiplanar reformation and automatic centerline positioning enables more accurate assessment of the maximum aortic diameter. Modern imaging techniques such as 4D flow MRI have the potential to further improve individualized risk stratification in patients with AAA. Key points:

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Increased Risk of Peripheral Arterial Disease in Patients With Abdominal Aortic Aneurysm: A Retrospective Cohort Study (Version 5)

Cited by 5 publications

References 38 publications

The Association Between Abdominal Aortic Aneurysms With Cardiovascular and Noncardiovascular Diseases

The Association Between Abdominal Aortic Aneurysms With Cardiovascular and Noncardiovascular Diseases

Screening for Abdominal Aortic Aneurysms and Risk Factors in 65-Year-Old Men in Oslo, Norway

Current Imaging Strategies in Patients with Abdominal Aortic Aneurysms

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