Increased Serum Uric Acid Association with Hypertension

Qabulio, Sumera Nawaz; Shahnawaz, Saba; Mansoor, Kanan; Jadoon, Aisha Khan; Akhter, Sohail; Tanwir, Farzeen

doi:10.29011/2475-5605.000043

Cited by 1 publication

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“…Previous studies [2][3][4][5][6] reported rising prevalence of hyperuricemia in low and middle-income countries populations. Many of previous studies [3][4][5][6][7] had reported correlation of hyperuricemia, systemic hypertension and obesity. Since research is lacking regarding the association of serum uric acid and systemic hypertension in Pakistan, this motivated the researcher to conduct the present study.…”

Section: Introductionmentioning

confidence: 95%

“…Pre-hypertension shows predilection for the hyperuricemia too. Previous studies 3,4 reported correlation of hyperuricemia and risk of systemic hypertension. Hyperuricemia has been linked to microalbuminuria in systemic hypertension and pre-hypertension.…”

Section: Introductionmentioning

confidence: 97%

“…2 Hyperuricemia has been reported as a risk factor for the systemic hypertension. [2][3][4][5] Previous studies 5,6 reported 25-50% of systemic hypertension cases show hyperuricemia. Hyperuricemia is now an established risk factor for the insulin resistance, weight gain and obesity, hyperlipidemia and dyslipidemia, kidney and systemic hypertension.…”

Section: Introductionmentioning

confidence: 99%

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Hyperuricemia in Systemic Hypertension and its correlation with systolic and diastolic blood pressure.

Khoharo

Shah

Qureshi

et al. 2020

TPMJ

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Objectives: To determine the serum uric acid (SUA) in systemic hypertension and its correlation with systolic (SBP) and diastolic blood pressure (DBP). Study Design: Cross sectional study design. Setting: Department of Medicine, Isra University Hospital. Period: From April 2016 – February 2017. Material and Methods: A sample of 100 cases of systemic hypertension and 100 age, gender, body weight and BMI controls were selected through non-probability purposive sampling. Volunteers were asked for history, physical examination, and blood sampling. Systemic BP was measured with a mercury sphygmomanometer. 2 ml venous blood was taken, centrifuged and sera were used for detection of SUA. Data was saved in a pre- structured Performa. Computed based statistical software (SPSS v 22.0, IBM, Incorporation, USA) was used for data analysis. Data variables were analyzed at 95% CI (P ≤ 0.05). Results: Serum uric acid in controls was 2.91±0.75 mg/dl compared to 5.70±1.76 mg/dl (P=0.0001). 57% of cases revealed hyperuricemia compared to 11% in control (X2=17.5, P=0.0001). Serum Uric acid showed significantly positive correlation with Systolic BP (r= 0.518*, p=0.0001) and Diastolic BP (r= 0.397**, p=0.0001). Conclusion: The present study reports hyperuricemia in 57% cases of systemic hypertension and uric acid shows positive correlation with systolic and diastolic blood pressure.

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