2016
DOI: 10.1089/aid.2016.0150
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Increased Steady-State Memory B Cell Subsets Among High-Risk Participants in an HIV Vaccine Trial

Abstract: The success of an HIV vaccine will require induction of a protective immune response in the most at-risk populations. The increased incidence of HIV infection in high-risk populations is assumed to be primarily the result of more frequent exposure to the virus or a greater inoculum of the virus; however, underlying variations in immune homeostasis may also contribute to HIV susceptibility and potentially impact vaccine responses and those required for protection. As an effective humoral immune response is like… Show more

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