Increasing global burden of rheumatoid arthritis: an epidemiological analysis from 1990 to 2019

Zou, W.; Fang, Yu; Xu, Dan; Zhu, Yimei

doi:10.5114/aoms/162629

Cited by 2 publications

(1 citation statement)

References 15 publications

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“…The disease is one of the main causes of human labor loss and disability. If it is not diagnosed and treated in time, 70% of the patients will be disabled after 2 years, and the average life expectancy will be shortened by 10–15 years [ 7 , 8 ]. Therefore, the treatment and nursing care of RA is the current focus of medical scientists.…”

Section: Introductionmentioning

confidence: 99%

Anemia in elderly rheumatoid arthritis patients: a cohort study

Sun,

Shao,

Liu

et al. 2023

Arch Med Sci

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IntroductionAnemia is common in elderly patients with rheumatoid arthritis (RA). This study aimed to evaluate the current status and influencing factors of anemia in RA patients, to provide insights for clinical RA treatment and care.Material and methodsThis study included elderly patients with high RA activity treated in our hospital from June 1, 2021 to December 31, 2022 for analysis. The characteristics of RA patients were analyzed. Pearson correlation and logistic regression analysis were conducted to analyze the influencing factors of anemia in elderly patients with RA.ResultsA total of 285 RA patients were included. The incidence of anemia in high RA activity patients was 62.46%. There were significant differences in the course of RA, hemoglobin (Hb), low density lipoprotein cholesterol (LDL-C), platelet/lymphocyte rate (PLR) and albumin (Alb) between RA patients with anemia and without anemia (all p < 0.05). Pearson correlation analysis indicated that course of RA (r = 0.522), Hb (r = 0.797), LDL-C (r = 0.558), PLR (r = 0.615) and Alb (r = 0.604) were correlated with anemia in patients with high RA activity (all p < 0.05). Logistic regression analysis indicated that course of RA ≥ 8 years (OR = 2.584, 95% CI: 1.822–3.647), LDL-C ≤ 2.8 mmol/l (OR = 3.202, 95% CI: 2.804–3.431), PLR ≥ 8 (OR = 2.183, 95% CI: 1.744–2.457), Alb ≤ 35 g/l (OR = 1.716, 95% CI: 1.401–2.006) were the risk factors of anemia in elderly patients with high RA activity (all p < 0.05).ConclusionsAnemia in elderly patients with high RA activity is closely related to the course of RA, LDL-C, PLR and Alb. Close attention should be paid to the monitoring of those indicators to take early intervention measures to improve the prognosis of RA patients.

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Section: Introductionmentioning

confidence: 99%