2019
DOI: 10.1016/j.eclinm.2019.05.007
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Increasing Hospitalization Rates for Cirrhosis: Overrepresentation of Disadvantaged Australians

Abstract: Background Limited information is available about hospitalization rates for cirrhosis in Australia. Methods Using information on all hospital episodes of care for patients admitted to Queensland hospitals during 2008–2016, we report age-standardized hospitalization rates/10,000 person-years, in-hospital case-fatality rate among these admissions (n = 30,327), and examine the factors associated with hospital deaths using logistic regression analyses. Findin… Show more

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Cited by 43 publications
(76 citation statements)
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References 25 publications
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“…Liver disease also contributed to aeromedical retrievals for GI disorders (3.6%; n = 217). This finding is consistent with research that indicates that rural and remote populations have higher rates of untreated hepatitis C and increased prevalence of excessive alcohol consumption, both of which are linked to liver cirrhosis and cancer . This, coupled with the increasing rates of substance use disorders requiring aeromedical retrieval, indicates a complex clinical environment …”
Section: Discussionsupporting
confidence: 89%
“…Liver disease also contributed to aeromedical retrievals for GI disorders (3.6%; n = 217). This finding is consistent with research that indicates that rural and remote populations have higher rates of untreated hepatitis C and increased prevalence of excessive alcohol consumption, both of which are linked to liver cirrhosis and cancer . This, coupled with the increasing rates of substance use disorders requiring aeromedical retrieval, indicates a complex clinical environment …”
Section: Discussionsupporting
confidence: 89%
“…In Australia, hospital admissions for cirrhosis increased by 61.7% during 2008-2016, with alcohol misuse a cause or contributing factor for cirrhosis in over half the admissions. (12) Importantly, the burden of T2D as a comorbidity in these patients has also been increasing, with an increase in prevalence of T2D from 13.7% in 2008-2010 to 25.4% in 2014-2016. (12) Although there is evidence that T2D impacts adversely on liver-related mortality, its influence on hospital readmissions and development of complications in patients with cirrhosis (particularly in ALD, the most common etiological factor among Australian hospital admissions for cirrhosis) has not been well studied.…”
Section: 3mentioning
confidence: 99%
“…(12) Importantly, the burden of T2D as a comorbidity in these patients has also been increasing, with an increase in prevalence of T2D from 13.7% in 2008-2010 to 25.4% in 2014-2016. (12) Although there is evidence that T2D impacts adversely on liver-related mortality, its influence on hospital readmissions and development of complications in patients with cirrhosis (particularly in ALD, the most common etiological factor among Australian hospital admissions for cirrhosis) has not been well studied. In this population-based study, we examined the association between T2D and patient outcomes (survival and readmission) among patients admitted for cirrhosis in the state of Queensland, Australia.…”
Section: 3mentioning
confidence: 99%
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“…However, the four major causes of cirrhosis in Australia are non‐alcoholic fatty liver disease, alcohol‐related liver disease, hepatitis C infection, and hepatitis B infection . At least 50% of patients with cirrhosis have at least two of these causes . Pharmaceutical Benefits Scheme‐funded treatments for hepatitis C will result in a reduction of HCC related to this cause in the next 10 years .…”
Section: Can We Prevent Hcc?mentioning
confidence: 99%