Increasing lateral tibial slope: is there an association with articular cartilage changes in the knee?

Khan, Nasir; Shepel, Michael; Leswick, David A.; Obaid, Haron

doi:10.1007/s00256-013-1800-7

Cited by 10 publications

(6 citation statements)

References 17 publications

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“…Prior work has shown that increased posterior–inferior directed slope of the tibial plateau is associated with increased risk of suffering an ACL and ACL graft injury, and the increased lateral compartment posterior–inferior directed slopes found in the current study (3.6° for the ACL‐LM group and 1.6 for the ACL group) further exacerbates the chance of a second injury to the ACL graft . In addition, there is evidence that geometry of the articular cartilage and tibial plateau subchondral bone are associated with worsening cartilage degenerative changes in the lateral tibial plateau . Considered in combination, these findings introduce the hypothesis that once ACL injury has occurred, the same geometric characteristics associated with increased risk of suffering the index injury—increased posterior–inferior directed slope of the articular surfaces of the tibia—are also associated with increased risk of developing PTOA.…”

Section: Discussionsupporting

confidence: 63%

“…[24][25][26] In addition, there is evidence that geometry of the articular cartilage and tibial plateau subchondral bone are associated with worsening cartilage degenerative changes in the lateral tibial plateau. 27 Considered in combination, these findings introduce the hypothesis that once ACL injury has occurred, the same geometric characteristics associated with increased risk of suffering the index injury-increased posterior-inferior directed slope of the articular surfaces of the tibia 10,[17][18][19] -are also associated with increased risk of developing PTOA. If future work supports this hypothesis, our finding of a twofold increase in slope for the combined ACL-LM group in comparison to the isolated ACL group may provide a biomechanical explanation for why the risk of PTOA is greater for those that suffer combined injuries to the ACL and meniscus in comparison to those that suffer isolated ACL trauma.…”

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confidence: 97%

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Combined Injury to the ACL and Lateral Meniscus Alters the Geometry of Articular Cartilage and Meniscus Soon After Initial Trauma

Beynnon

Fiorentino

Gardner‐Morse

et al. 2019

Journal Orthopaedic Research

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Combined injury to the anterior cruciate ligament (ACL) and meniscus is associated with earlier onset and increased rates of post‐traumatic osteoarthritis compared with isolated ACL injury. However, little is known about the initial changes in joint structure associated with these different types of trauma. We hypothesized that trauma to the ACL and lateral meniscus has an immediate effect on morphometry of the articular cartilage and meniscus about the entire tibial plateau that is more pronounced than an ACL tear without meniscus injury. Subjects underwent magnetic resonance imaging scanning soon after injury and prior to surgery. Those that suffered injury to the ACL and lateral meniscus underwent changes in the lateral compartment (increases in the posterior–inferior directed slopes of the articular cartilage surface, and the wedge angle of the posterior horn of the meniscus) and medial compartment (the cartilage‐to‐bone height decreased in the region located under the posterior horn of the meniscus, and the thickness of cartilage increased and decreased in the mid and posterior regions of the plateau, respectively). Subjects that suffered an isolated ACL tear did not undergo the same magnitude of change to these articular structures. A majority of the changes in morphometry occurred in the lateral compartment of the knee; however, change in the medial compartment of the knee with a normal appearing meniscus also occurred. Statement of clinical significance: Knee injuries that involve combined trauma to the ACL and meniscus directly affect both compartments of the knee, even if the meniscus and articular cartilage appears normal upon arthroscopic examination. © 2019 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 38:759‐767, 2020

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Section: Discussionsupporting

confidence: 63%

mentioning

confidence: 97%

Combined Injury to the ACL and Lateral Meniscus Alters the Geometry of Articular Cartilage and Meniscus Soon After Initial Trauma

Beynnon

Fiorentino

Gardner‐Morse

et al. 2019

Journal Orthopaedic Research

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“…As the angle decreases, there is an increased risk of graft impingement, which in turn increases tibiofemoral and patellofemoral contact load and ultimately accelerates cartilage degeneration ( Shelbourne et al, 2017 ). Mitchell found that the decrease of tibial plateau posterior inclination was related to medial femoral compartment cartilage injury ( Mitchell et al, 2018 ), which was different from previous studies, which showed increased tibial plateau posterior inclination caused cartilage injury ( Khan et al, 2014 ). However, the mechanism leading to this difference has not been clarified.…”

Section: Risk Factors Of Cartilage Lesioncontrasting

confidence: 65%

Risk factors of cartilage lesion after anterior cruciate ligament reconstruction

Huang

Cui

Zhong

et al. 2022

Front. Cell Dev. Biol.

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Anterior cruciate ligament injury is the most common sports injury in orthopaedics, which can adversely affect knee joint function and exercise of patients. Using arthroscopy to reconstruct the anterior cruciate ligament has become the first choice for treating anterior cruciate ligament rupture. However, different degrees of articular cartilage injury of the knee can be observed in patients after anterior cruciate ligament reconstruction. More importantly, the articular cartilage injury after anterior cruciate ligament reconstruction indicates that it will develop into osteoarthritis in the long term. It is of great significance to fully understand the factors that lead to the occurrence and development of cartilage injury. This article reviews the effects of surgical methods, meniscus status, different grafts, time from injury to surgical intervention, postoperative knee joint stability, postoperative rehabilitation, knee joint anatomical factors, and demographic characteristics of patients on articular cartilage degeneration after anterior cruciate ligament reconstruction. The present review provides insights into the anterior cruciate ligament reconstruction, which can be used to investigate new treatment strategies to delay and prevent the progress of osteoarthritis. At the same time, it provides a holistic understanding of the influence of multiple factors on cartilage lesions after anterior cruciate ligament reconstruction.

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“…Increased posterior tibia slope has been suggested as not only a risk factor for initial ACL injury and the failure of ACLR graft 9,10 , but also a risk factor for OA 11 . Increased posterior tibia slope, as indicated by Tibia 7, was observed in this study especially from 6M to 1Y.…”

Section: Discussionmentioning

confidence: 99%

3D bone-shape changes and their correlations with cartilage T1ρ and T2 relaxation times and patient-reported outcomes over 3-years after ACL reconstruction

Zhong

Pedoia

Tanaka

et al. 2019

Osteoarthritis and Cartilage

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Purpose: (1) To identify bone-shape changes from baseline to 3-years after anterior cruciate ligament reconstruction (ACLR). (2) to assess association between changes in bone-shape from baseline to 6-months and changes in cartilage matrix and patient functions and symptoms from baseline to 3-years after ACLR. Methods: Bilateral knees of 30 patients with unilateral ACL injuries were scanned at baseline, 6-months, 1-, 2-, and 3-years after ACLR. Bilateral knees of 13 controls were scanned at baseline, 1-and 3-years. Mean T1r and T2 values of each cartilage compartment were computed. Bone shape was quantified using statistical shape modeling (SSM) and 3D-MRI. Patient functions and symptoms were evaluated using Knee Injury and Osteoarthritis Outcome Score (KOOS). Results: Statistically significant changes were observed in Femur 2 (medial femoral condyle [MF] shape), Femur 6 (intercondylar notch width), Tibia 1 (tibia plateau area), and Tibia 7 (medial tibia slope) over 3-years after ACLR. Statistically significant differences were observed between injured and control knees in several modes. Statistically significant correlations were found between changes in bone shape (DFemur 6, DFemur 8 [trochlea inclination and MF height], DTibia 1) from baseline to 6-months and that of cartilage T1r and T2 and KOOS from baseline to 3-years after ACLR. Conclusion: Bone shape remodeling occurs after ACLR, and early bone shape changes (within 6 months) correlated with cartilage matrix and patient outcomes at 3-years after ACLR. Bone shape can be a promising imaging biomarker that stratifies patients at high risk for post-traumatic osteoarthritis (PTOA).

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Increasing lateral tibial slope: is there an association with articular cartilage changes in the knee?

Cited by 10 publications

References 17 publications

Combined Injury to the ACL and Lateral Meniscus Alters the Geometry of Articular Cartilage and Meniscus Soon After Initial Trauma

Combined Injury to the ACL and Lateral Meniscus Alters the Geometry of Articular Cartilage and Meniscus Soon After Initial Trauma

Risk factors of cartilage lesion after anterior cruciate ligament reconstruction

3D bone-shape changes and their correlations with cartilage T1ρ and T2 relaxation times and patient-reported outcomes over 3-years after ACL reconstruction

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