Increasing plasma lysophosphatidylcholine levels in patients with regular dextran sulfate lipoprotein apheresis

Graessler, Juergen; Schuhmann, Kai; Shevchenko, Andrej; Kopprasch, Steffi; Ban, Ryan H.; Bergmann, S.; Bornstein, Stefan R.; Hohenstein, Bernd; Julius, Ulrich

doi:10.1016/j.atherosclerosissup.2015.02.026

Cited by 2 publications

(1 citation statement)

References 24 publications

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“…As we can see, these diseases include cancer , vascular diseases , DM , neuropsychiatric disorders , and so on. Besides, serum or plasma from human or animal models is the main sample materials for lipidomic analysis, as well as tissues and cells . Among the various diseases, cancer, atherosclerosis, DM, and AD have been concerned extensively in lipidomic research.…”

Section: Lipidomics In Disease Researchmentioning

confidence: 99%

Recent advances in lipidomics for disease research

Yang

Shan

et al. 2015

J of Separation Science

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Lipidomics is an important branch of metabolomics, which aims at the detailed analysis of lipid species and their multiple roles in the living system. In recent years, the development of various analytical methods for effective identification and characterization of lipids has greatly promoted the process of lipidomics. Meanwhile, as many diseases demonstrate a remarkable alteration in lipid profiles compared with that of healthy people, lipidomics has been extensively introduced to disease research. The comprehensive lipid profiling provides a chance to discover novel biomarkers for specific disease. In addition, it plays a crucial role in the study of lipid metabolism, which could illuminate the pathogenesis of diseases. In this review, after brief discussion of analytical methods for lipidomics in clinical research, we focus on the recent advances of lipidomics related to four types of diseases, including cancer, atherosclerosis, diabetes mellitus, and Alzheimer's disease.

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