Increasing pre-transplant confidence and safety for use of questionable donor lungs with <i>ex-situ</i>
 assessment and reconditioning

Raemdonck, Dirk Van; Neyrinck, Arne

doi:10.1111/tri.13375

Cited by 1 publication

(1 citation statement)

References 20 publications

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“…Single-center success using EVLP as a tool for evaluating marginal organs was well documented, [33][34][35] and overviews of EVLP clinical trials and future possibilities continued to expand. [36][37][38][39][40][41][42] Biomarkers of EVLP perfusate correlated with early outcomes and offered prognostic value prior to organ implantation. 43 Pulmonary hemodynamics during EVLP were associated with inflammatory responses and offered additional information about graft suitability above what is provided by arterial blood gas and pulmonary vascular resistance measures.…”

Section: Lung Transplantationmentioning

confidence: 99%

Noteworthy Literature Published in 2018 for Thoracic Organ Transplantation

Tawil

Adams

Nicoara

et al. 2019

Semin Cardiothorac Vasc Anesth

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Publications of note from 2018 are reviewed for the cardiothoracic transplant anesthesiologist. Strategies to expand the availability of donor organs were highlighted, including improved donor management, accumulating experience with increased-risk donors, ex vivo perfusion techniques, and donation after cardiac death. A number of reports examined posttransplant outcomes, including outcomes other than mortality, with new data-driven risk models. Use of extracorporeal support in cardiothoracic transplantation was a prominent theme. Major changes in adult heart allocation criteria were implemented, aiming to improve objectivity and transparency in the listing process. Frailty and prehabilitation emerged as targets of comprehensive perioperative risk mitigation programs.

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