Increasing prevalence and dissemination of invasive nontyphoidal Salmonella serotype Typhimurium with multidrug resistance in hospitalized patients from southern Brazil

Abstract

Greater public health attention should be given to prevent salmonellosis in the community and in hospital settings to reduce the rates of Typhimurium strains with multidrug resistance.

Characterization of non-typhoidal Salmonella isolates from children with acute gastroenteritis, Kolkata, India, during 2000–2016

“…Bassal et al reported predominance of S. Infantis over S. Enteritidis (1999Enteritidis ( -2008 in Israel post 2008 [57]. The shift from S. Enteritidis (2010) to S. Typhimurium (2011-2015) as the predominant serovar among humans was also reported from southern Brazil [58]. Changes in meteorology, human food habits, international travel, and trade have been associated with the temporal dominance of certain serotypes followed by a decline and replacement with another [52,57].…”

Plasmid-borne colistin resistance gene mcr-1 in a multidrug resistant Salmonella enterica serovar Typhimurium isolate from an infant with acute diarrhea in China

“…Moreover, S. Typhimurium is the second most prevalent serotype in China (Lu et al, 2011). Some studies had found that S. Typhimurium was exhibiting a multi-drug resistance pattern and carried a large number of virulence genes (Reis et al, 2018;Xiang et al, 2020). With the emergence of antimicrobialresistant Salmonella, the epidemic multidrug-resistant (MDR) S. Typhimurium strain definitive phage type 104 (DT104), first observed during the 1990s (Mølbak et al, 1999), became increasingly prevalent.…”

Frequency of Antimicrobial Resistance Genes in Salmonella From Brazil by in silico Whole-Genome Sequencing Analysis: An Overview of the Last Four Decades

“…Although the selection of antimicrobial-resistant bacteria is a natural process, the therapeutic use and the misuse of antimicrobial drugs in humans and animals have increased the selective pressure through the last decades ( O’Neill, 2016 ). In addition, a large number of pathogenic bacteria, such as Salmonella , due to constant exposure to several different antimicrobial drugs, have recently been selected for resistance against one or more of these agents ( dos Reis et al, 2018 ; Collignon and McEwen, 2019 ; Van Boeckel et al, 2019 ; Rabello et al, 2020 ). The current development lack of novel antimicrobials to replace the first-generation drugs brings the urgency to preserve the efficacy of existing drugs through the judicious use of antimicrobials.…”