Increasing prevalence of advanced colonic polyps in young patients undergoing colonoscopy in a referral academic hospital in Hong Kong

Lam, T. J.; Wong, Benjamin Chun–Yu; Mulder, Chris J.; Peña, A. S.; Hui, W. M.; Lam, Shiu Kum; Chan, Annie On On

doi:10.3748/wjg.v13.i28.3873

Cited by 10 publications

(7 citation statements)

References 26 publications

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“…The polyps and ANL were found predominantly in the recto-sigmoid colon. This finding is consistent with other studies, where the left colon is the principal site of ANL and polyps [23][24][25].…”

Section: Discussionsupporting

confidence: 93%

“…However, polyps were seen more often in men than in women. The increasing prevalence of polyps in young male patients was already observed in a recently published study [24].…”

Section: Discussionsupporting

confidence: 59%

“…Krones et al [19] looked retrospective at resected specimen for CRC for diverticulitis and in resected diverticulitis for ANP. In the CRC group, the incidence of diverticulosis was only 18% and ANP in the diverticulitis group only 6%, both very low numbers [23][24][25]. Subsequently, a negative relationship was found.…”

Section: Discussionmentioning

confidence: 90%

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Diverticulosis and diverticulitis form no risk for polyps and colorectal neoplasia in 4,241 colonoscopies

Meurs-Szojda

Droste

Kuik

et al. 2008

Int J Colorectal Dis

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Background and aims There are conflicting data concerning the association between diverticular disease and colorectal carcinoma (CRC). This study was performed to determine the prevalence and association of diverticulosis, diverticulitis, polyps, and CRC. Materials and methods In a cross-sectional, retrospective study, we analyzed the colonoscopy reports of complete colonoscopies and patho-histological results of all patients referred for colonoscopy in a period of 3 months in 18 hospitals in The Netherlands. Diverticulosis was defined as three or more diverticula present and diverticulitis as diverticulosis with inflammation. Polyps were also coded according to localization and size. Advanced neoplastic lesions were defined as polyps ≥10 mm in diameter and/or villous architecture and/or adenomas with high grade dysplasia and/or invasive cancer. Actual and previous described CRC were registered. Results A total of 4,241 patients were included in the study [1,996 (47%) male], mean age of 59 and range 18-95. Diverticula, diverticulitis, and polyps were seen in 1,052 (25%), 75 (2%), and 1,282 (30%) patients, respectively. No association was found between patients with polyps and those with and without diverticulosis (p=0.478). Invasive adenocarcinoma and adenomas ≥10 mm were most frequently observed. CRC was present in 372 (9%) patients. Negative relation between diverticulosis and CRC and invasive adenocarcinoma was observed. No association was found between polyps and CRC and patients with diverticulitis and CRC. In conclusion, there is no relation between patients with diverticulosis and higher incidence of polyps or CRC when using age-stratified analysis. No increased risk for polyps or CRC was found in patients with diverticulitis.

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Section: Discussionsupporting

confidence: 93%

“…However, polyps were seen more often in men than in women. The increasing prevalence of polyps in young male patients was already observed in a recently published study [24].…”

Section: Discussionsupporting

confidence: 59%

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Diverticulosis and diverticulitis form no risk for polyps and colorectal neoplasia in 4,241 colonoscopies

Meurs-Szojda

Droste

Kuik

et al. 2008

Int J Colorectal Dis

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“…This was in concordance with study conducted by Thura et al 15 and Franklin et al 16 The age group affected by adenoma in our study ranged from 31 years to 73 years with a mean age of 60-78 years, with male predominance (66.6%).Male to female ratio is 2:1 which is in concordance with the National polyp study where adenoma occurred more frequently in men than women 61.6% versus 38.4%. 17 The most common adenoma encountered was tubular adenoma (44%) followed by tubulovillous and villous adenoma which was in concordance with the study conducted by Thomas et al, 18 Gillespie et al 19 and Tze Jui et al 20 Villous adenoma was seen in patients older than 55 years of age. 44.4% of patients with adenoma had associated colorectal carcinoma.…”

Section: Discussionsupporting

confidence: 78%

A Study of Spectrum of Histopathological Lesions in Colon in a Tertiary Care Centre in South Karnataka

Raju¹,

Teerthanath²

2019

jebmh

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BACKGROUND Histopathological study of colonoscopic biopsies is a well-established and cost-effective diagnostic test for evaluation of colonic lesions. It also contributes significantly to the pre-operate investigation of patients with colonic lesions .The main objective of the study is to scrutinize all colonoscopy biopsies and to study the Histopathology of colonic lesions and the spectrum of various colonic lesions and their prevalence in patients presenting to tertiary care hospital in South Karnataka. A total of 150 colonoscopic biopsies was studied in a 2-year period in the Department of Pathology, K. S. Hedge Medical Academy. METHODS Patients presenting with symptoms of pain abdomen, chronic altered bowel habits, haematochezia were examined by flexible colonoscopy after receiving consent from the patient. Biopsy specimen were mounted on a filter paper, fixed in formalin (10% solution of formaldehyde) and then processed. Sections of 3-4 µ were mounted on a clean glass side and stained with haematoxylin and eosin (H&E) stain. Special stains like PAS, GMS, MTS, Ziehl Neelsen (ZN) etc., were used whenever indicated. RESULTS Age of the patients ranged from 3 years to 87 years with a mean age of 47.65 years. Majority of the patients were males (83 cases) with a male to female ratio of 1.23:1. Among 150 cases, 92 cases (61.3%) were non neoplastic lesions and 58 cases (38.7%) were neoplastic lesion. The ratio of non-neoplastic to neoplastic lesion was 1.58:1. CONCLUSIONS The incidence of colonic lesions is increasing in recent years with early onset of inflammatory bowel disease and colorectal neoplasm in relatively younger age group due to changing life style and dietary habits.

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“…In addition, both diseases share a similar distribution. Although a gradual shift toward right‐sided colonic lesions has been observed, most of them are mainly left‐sided [14,15]. Diverticulitis develops commonly in the left colon as well, especially in the sigmoid [16].…”

Section: Introductionmentioning

confidence: 99%

There is no increased risk for colorectal cancer and adenomas in patients with diverticulitis: a retrospective longitudinal study

Lam¹,

Meurs-Szojda²,

Gundlach³

et al. 2009

Colorectal Disease

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Increasing prevalence of advanced colonic polyps in young patients undergoing colonoscopy in a referral academic hospital in Hong Kong

Cited by 10 publications

References 26 publications

Diverticulosis and diverticulitis form no risk for polyps and colorectal neoplasia in 4,241 colonoscopies

Diverticulosis and diverticulitis form no risk for polyps and colorectal neoplasia in 4,241 colonoscopies

A Study of Spectrum of Histopathological Lesions in Colon in a Tertiary Care Centre in South Karnataka

There is no increased risk for colorectal cancer and adenomas in patients with diverticulitis: a retrospective longitudinal study

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