Increasing rabies data availability: The example of a One Health research project in Chad, Côte d'Ivoire and Mali

Léchenne, Monique; Traoré, Abdallah; Hattendorf, Jan; Kallo, Vessaly; Oussiguéré, Assandi; Tetchi, Mathilde; Moyengar, Ronelngar; Traoré, Abdel Kader; Moto, Daugla Doumagoum; Ngandolo, Richard; Bonfoh, Bassirou; Zinsstag, Jakob

doi:10.1016/j.actatropica.2020.105808

Cited by 19 publications

(34 citation statements)

References 54 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…According to the Stepwise Approach toward rabies elimination, integrating the One Health approach into rabies control strategies can enable effective surveillance through data collection, reporting, and information sharing across sectors. Moreover, multisectoral collaboration can increase vaccination coverage in the canine population, availability of and accessibility to post-exposure prophylaxis, awareness and education of the general public, and availability of laboratory testing for humans and animals [22,[25][26][27].…”

Section: Discussionmentioning

confidence: 99%

Adoption of the One Health approach to improve zoonosis control in low-income countries: Insights from the case of rabies management in Burkina Faso

et al. 2021

View full text Add to dashboard Cite

Background and Aim: Rabies is a neglected zoonotic disease transmissible to humans and domestic and wild animals through biting, scratching, or licking. This study aimed to analyze the adoption of the One Health approach by the stakeholders involved in rabies control in Burkina Faso. Materials and Methods: The stakeholders involved in rabies control were from the Ministry of Livestock, Ministry of Health, Ministry of the Territory Administration, Ministry of Environment and Wildlife, and Ministry of Higher Education and Research. A structured questionnaire was used in face-to-face interviews to collect data from the stakeholders. The collected data included stakeholders' knowledge of rabies and the One Health approach and their levels of involvement in the multisectoral collaboration. Results: Most participants could not describe rabies correctly (80%), and only 52.9% had heard of the One Health approach. In addition, there was no significant association between knowledge of rabies and participants' characteristics, and the knowledge of the One Health approach was significantly influenced by a participant's affiliation (place of work). Conclusion: The results call for an increase in One Health education for its effective adoption by all the rabies control stakeholders. Additional efforts should focus on continual training of the One Health workforce, from policy-makers to frontline personnel.

show abstract

Section: Discussionmentioning

confidence: 99%

Adoption of the One Health approach to improve zoonosis control in low-income countries: Insights from the case of rabies management in Burkina Faso

et al. 2021

View full text Add to dashboard Cite

show abstract

“…The qualitative study presented in this paper is part of a large-scale research project implemented in Chad, Côte d'Ivoire and Mali, to estimate the burden of rabies and vaccine demand in West and Central Africa, funded by GAVI described in Léchenne et al ( 20 ). In Chad, this research project lasted from January 2016 to September 2018 and was implemented in three study areas belonging to four administrative provinces (see chapter Study areas below).…”

Section: Methodsmentioning

confidence: 99%

“…On the institutional level, 57 providers participated in the study, 35% (20) in Logone Occidental, 42% (24) in Ouaddaï and 23% (13) in rural N'Djamena. There were 84% (48) from the human health and 16% (9) from the veterinary health sector.…”

Section: Characteristics Of the Participantsmentioning

confidence: 99%

“…From 2016 to 2018, a project to estimate the burden of rabies and PEP demand in West and Central Africa was conducted with financial support from GAVI ( 20 ). In Chad, this funding has enabled the extension of canine rabies surveillance to four administrative provinces through establishment of decentralized diagnostic units ( 21 ), collection of data on bite exposure on household level and access to PEP on health facility level ( 18 ).…”

Section: Introductionmentioning

confidence: 99%

“…With regard to rabies service delivery, human and veterinary health personnel were not used to collaborate for the management of bite victims, prior to the GAVI project. During the project a OH approach was piloted in the study regions with the aim to improve communication between the human and animal health sector ( 20 ). Despite this effort, among overall 1,540 bite cases reported during the health facility survey, only 20% had been the subject of effective collaboration between human and veterinary health services ( 18 ), which illustrates the persistence of communication difficulties between the two sectors even after reinforcement through an OH project.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

“When a dog bites someone”: Community and service provider dynamics influencing access to integrated bite case management in Chad

et al. 2022

Self Cite

View full text Add to dashboard Cite

This study aims to identify factors on the community, the human health and the animal health provider level that determine access to Post Exposure Prophylaxis (PEP) and animal rabies diagnosis in the light of a future integrated bite case management (IBCM) approach for rabies control in Chad. The study was embedded in an overall project conducted from 2016 to 2018, to determine rabies burden and vaccine demand in West and Central Africa. Data collection took place during the projects closing workshops with stakeholders organized between August and September 2018 in the three study zones in Chad covering Logone Occidental and Ouaddaï province and parts of Hadjer Lamis and Chari Baguirmi province. A qualitative approach based on focus group discussion and in-depth interviews was used to get insights on access to care and animal investigation after suspected rabies exposure. A total of 96 participants, including 39 from the community (bite victims, dog owners) and 57 human and animal health providers (health center managers, chief veterinary officers, chief district medical officers, chiefs of livestock sectors) contributed to the study. Based on an existing conceptual framework of access to health care, several points of dissatisfaction were identified, in particular the unaffordability of human rabies vaccine for PEP (affordability) and the distance to travel to a health facility in case of a bite (accessibility). In addition, there are unfavorable attitudes observed highlighted by the importance given to traditional or local rabies care practices to the detriment of PEP (acceptability) and a low level of knowledge among Chadian communities regarding bite prevention, coupled with a very inadequate information and awareness system regarding the disease (adequacy). As for human and veterinary health services, both sectors suffer from insufficient resources for PEP on the human health and rabies diagnosis on the veterinary side impacting negatively on availability and accessibility of both these services. Action to improving provision of rabies health services and increasing knowledge about risk and prevention of the disease among the population need to be undertaken to implement IBCM, improve access to PEP and achieve the goal of eliminating dog mediated human rabies by 2030 in Chad.

show abstract

Regulation of innate immune responses by rabies virus

Zhang

Huang

Song

et al. 2022

Anim Models and Exp Med

View full text Add to dashboard Cite

Rabies is one of the oldest zoonotic diseases caused by rabies virus (RABV). It has been a global concern because after the symptoms of rabies appear, the mortality rate is close to 100%, and it ultimately leads to death; only a very few cases survive with serious sequelae.Although prevention and control of rabies has greatly improved globally and rabies cases are extremely rare in developed countries and regions, 1,2 it is still at a high level in many developing countries and less-developed countries, mainly concentrated in Africa and Asia. [3][4][5][6][7][8][9][10][11][12][13][14][15] According to the World Health Organization report in 2017, about 59 000 people die of rabies every year. Except for vaccination and emergency treatment with a specific antiserum after exposure, [16][17][18] there are no effective drugs for rabies. 19 The pathogenic mechanism of RABV and the relationship between the virus and host immune response are not thoroughly understood, leading to a lag in the development of therapeutic drugs.RABV has a wide host range with the ability to infect almost all warm-blooded animals. RABV is an enveloped, nonsegmented, single-stranded, negative-sense RNA virus and is classified in the

show abstract

Increasing rabies data availability: The example of a One Health research project in Chad, Côte d'Ivoire and Mali

Cited by 19 publications

References 54 publications

Adoption of the One Health approach to improve zoonosis control in low-income countries: Insights from the case of rabies management in Burkina Faso

Adoption of the One Health approach to improve zoonosis control in low-income countries: Insights from the case of rabies management in Burkina Faso

“When a dog bites someone”: Community and service provider dynamics influencing access to integrated bite case management in Chad

Regulation of innate immune responses by rabies virus

Contact Info

Product

Resources

About