2023
DOI: 10.21203/rs.3.rs-2825652/v1
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Increasing rectum–prostate distance using a hydrogel spacer to reduce radiation exposure during proton beam therapy for prostate cancer

Abstract: SpaceOAR®, a polyethylene-glycol hydrogel, reduces rectal radiation exposure during radiation therapy for prostate cancer. This study aimed to investigate the impact of our modified technique of hydrogel insertion, which achieves greater separated distance at prostate-apex, on radiation exposure reduction during proton beam therapy (PBT). We included 330 patients undergoing PBT with the relative biological effectiveness (RBE) of 63 Gray (Gy) for localized prostate cancer, and categorized them into groups 0 (no… Show more

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