Increasing the bioavailability of curcumin using a green supercritical fluid technology-assisted approach based on simultaneous starch aerogel formation-curcumin impregnation

Alavi, Farhad; Ciftci, Ozan N.

doi:10.1016/j.foodchem.2024.139468

Food Chemistry

2024

DOI: 10.1016/j.foodchem.2024.139468

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Increasing the bioavailability of curcumin using a green supercritical fluid technology-assisted approach based on simultaneous starch aerogel formation-curcumin impregnation

Farhad Alavi,

Ozan N. Ciftci

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2024

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Cited by 2 publications

References 41 publications

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Supercritical carbon dioxide as solvent for manufacturing of ibuprofen loaded gelatine sponges with enhanced performance

Li,

Zheng,

Zhang

et al. 2024

Chemical Engineering and Processing - Process Intensification

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Supercritical carbon dioxide as solvent for manufacturing of ibuprofen loaded gelatine sponges with enhanced performance

Li,

Zheng,

Zhang

et al. 2024

Chemical Engineering and Processing - Process Intensification

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Sustained Release of Curcumin from Cur-LPs Loaded Adaptive Injectable Self-Healing Hydrogels

Wu,

Ning,

Liu

et al. 2024

Polymers

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Biological tissue defects are typically characterized by various shaped defects, and they are prone to inflammation and the excessive accumulation of reactive oxygen species. Therefore, it is still urgent to develop functional materials which can fully occupy and adhere to irregularly shaped defects by injection and promote the tissue repair process using antioxidant and anti-inflammatory mechanisms. Herein, in this work, phenylboronic acid modified oxidized hyaluronic acid (OHAPBA) was synthesized and dynamically crosslinked with catechol group modified glycol chitosan (GCHCA) and guar gum (GG) into a hydrogel loaded with curcumin liposomes (Cur-LPs) which were relatively uniformly distributed around 180 nm. The hydrogel possessed rapid gelation within 30 s, outstanding injectability and tissue-adaptive properties with self-healing properties, and the ability to adhere to biological tissues and adapt to tissue movement. Moreover, good biocompatibility and higher DPPH scavenging efficiency were illustrated in the hydrogel. And a more sustainable release of curcumin from Cur-LPs-loaded hydrogels, which could last for 10 days, was achieved to improve the bioavailability of curcumin. Finally, they might be injected to fully occupy and adhere to irregularly shaped defects and promote the tissue repair process by antioxidant mechanisms and the sustained release of curcumin for anti-inflammation. And the hydrogel would have potential application as candidates in tissue defect repair.

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Increasing the bioavailability of curcumin using a green supercritical fluid technology-assisted approach based on simultaneous starch aerogel formation-curcumin impregnation

Cited by 2 publications

References 41 publications

Supercritical carbon dioxide as solvent for manufacturing of ibuprofen loaded gelatine sponges with enhanced performance

Supercritical carbon dioxide as solvent for manufacturing of ibuprofen loaded gelatine sponges with enhanced performance

Sustained Release of Curcumin from Cur-LPs Loaded Adaptive Injectable Self-Healing Hydrogels

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