Increasing trends of lung cancer in Golestan province, Northern Iran (2004–2016)

Khandashpour, Mahmoud; Naeimi-Tabiei, Mohammad; Ariannia, Ali; Ashaari, Mohammad; Sedaghat, Seyed Mehdi; Ghasemi-Kebria, Fatemeh; Salamat, Fatemeh; Moghaddami, Abbas; Hasanpour-Heidari, Susan; Hoseinpour, Reza; Weiderpass, Elisabete; Ghayoriardahaei, Hamid; Gholami, Masoumeh; Fazel, Abdolreza; Roshandel, Gholamreza; Ferlay, Jacques; Ferlay, Jacques

doi:10.1016/j.canep.2020.101687

Cited by 2 publications

(2 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The main cause of lung cancer is the exposure of the body to harmful, carcinogenic chemical substances [5][6][7]. It is believed that the most common and important risk factor for all histological types of lung cancer, responsible for the development of about 85% of all cases, is smoking [8][9][10][11][12].…”

Section: Introduction-lung Cancer Classificationmentioning

confidence: 99%

See 1 more Smart Citation

Role of SOX Protein Groups F and H in Lung Cancer Progression

Olbromski¹,

Podhorska‐Okołów

Dzięgiel

2020

Cancers

View full text Add to dashboard Cite

The SOX family proteins are proved to play a crucial role in the development of the lymphatic ducts and the cardiovascular system. Moreover, an increased expression level of the SOX18 protein has been found in many malignances, such as melanoma, stomach, pancreatic breast and lung cancers. Another SOX family protein, the SOX30 transcription factor, is responsible for the development of male germ cells. Additionally, recent studies have shown its proapoptotic character in non-small cell lung cancer cells. Our preliminary studies showed a disparity in the amount of mRNA of the SOX18 gene relative to the amount of protein. This is why our attention has been focused on microRNA (miRNA) molecules, which could regulate the SOX18 gene transcript level. Recent data point to the fact that, in practically all types of cancer, hundreds of genes exhibit an abnormal methylation, covering around 5–10% of the thousands of CpG islands present in the promoter sequences, which in normal cells should not be methylated from the moment the embryo finishes its development. It has been demonstrated that in non-small-cell lung cancer (NSCLC) cases there is a large heterogeneity of the methylation process. The role of the SOX18 and SOX30 expression in non-small-cell lung cancers (NSCLCs) is not yet fully understood. However, if we take into account previous reports, these proteins may be important factors in the development and progression of these malignancies.

show abstract

Section: Introduction-lung Cancer Classificationmentioning

confidence: 99%

“…Morbidity is the highest among non-smoking people, women and young people up to 45 years of age. In comparison to other types of NSCLC, AC and LSCC are usually located in a focuse, which enables more efficient and more effective anticancer therapies [2,5,8,34].…”

Section: Introduction-lung Cancer Classificationmentioning

confidence: 99%

Role of SOX Protein Groups F and H in Lung Cancer Progression

Olbromski¹,

Podhorska‐Okołów

Dzięgiel

2020

Cancers

View full text Add to dashboard Cite

show abstract

Incidence Trend of Lung Cancer in Iran: A Systematic Review and Meta-analysis

Bastani

Shokri

2023

Int J Cancer Manag

View full text Add to dashboard Cite

Context: Lung cancer (LC) is one of the common diseases in the pulmonary system, which is defined as the uncontrolled growth of cells in the lung tissue. Objectives: The present investigation was conducted with the aim of the prevalence of LC in Iran by meta-analysis method. Methods: In this meta-analysis study, the articles that were conducted to determine age-standardized incidence rates (ASRs) in the field of LC were included in the study. The inclusion criteria included determining the number of ASRs in Iranian LC patients, reporting the sample size in men and women groups, and publishing articles between 2000 and January 2023. Data were analyzed, using CMA software. Results: In this meta-analysis study, 889 articles were found in the initial search, and after the final search, 23 articles were included in the meta-analysis stage. Out of the 22 final articles, the prevalence of LC was 3.7% (95% CI, 2.6 - 5.3) in women and 7.1% (95% CI, 5.7 - 9) in males. Conclusions: Considering that the incidence rate of LC in this study was high, it is essential to carry out necessary preventive interventions in this field.

show abstract

Increasing trends of lung cancer in Golestan province, Northern Iran (2004–2016)

Cited by 2 publications

References 33 publications

Role of SOX Protein Groups F and H in Lung Cancer Progression

Role of SOX Protein Groups F and H in Lung Cancer Progression

Incidence Trend of Lung Cancer in Iran: A Systematic Review and Meta-analysis

Contact Info

Product

Resources

About