Incremental value of parametric quantitative assessment of myocardial perfusion by triggered Low-Power myocardial contrast echocardiography

Yu, Eric; Skyba, Danny M.; Leong‐Poi, Howard; Sloggett, Cairrine; Jamorski, Michal; Garg, Rohit; Iwanochko, Robert M.; Siu, Samuel C.

doi:10.1016/j.jacc.2003.09.073

Cited by 35 publications

(24 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Another possible solution to this problem is to collect triggered RTP images (Yu et al 2004), thus avoiding continuous ultrasound exposure, which would result in fewer apical perfusion artefacts. However, then the advantage of combining assessment of perfusion and wall motion would of course be lost.…”

Section: Discussionmentioning

confidence: 99%

Real‐time perfusion adenosine stress echocardiography versus myocardial perfusion adenosine scintigraphy for the detection of myocardial ischaemia in patients with stable coronary artery disease

Gudmundsson

Winter

Dencker

et al. 2005

Clin Physio Funct Imaging

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Real‐time perfusion adenosine stress echocardiography versus myocardial perfusion adenosine scintigraphy for the detection of myocardial ischaemia in patients with stable coronary artery disease

Gudmundsson

Winter

Dencker

et al. 2005

Clin Physio Funct Imaging

View full text Add to dashboard Cite

show abstract

“…Positron emission tomography (PET), computed tomography (CT), magnetic resonance imaging (MRI) and echocardiography have all demonstrated capabilities in assessing myocardial function by measuring perfusion of contrast agents into and out of the intercellular space of cardiac tissue (Gerber et al, 2002;Klein et al, 2002;Koyama et al, 2004;Lardo et al, 2000;Yu et al, 2004). However, the potential complications with the use of contrast agents as well as the cost of these imaging modalities are limiting factors for their widespread clinical application.…”

Section: Introductionmentioning

confidence: 99%

In Vivo Assessment of Myocardial Stiffness with Acoustic Radiation Force Impulse Imaging

Hsu¹,

Bouchard²,

Dumont³

et al. 2007

Ultrasound in Medicine & Biology

112

106

View full text Add to dashboard Cite

Acoustic radiation force impulse (ARFI) imaging has been demonstrated to be capable of visualizing variations in local stiffness within soft tissue. Recent advances in ARFI beam sequencing and parallel imaging have shortened acquisition times and lessened transducer heating to a point where ARFI acquisitions can be executed at high frame rates on commercially available diagnostic scanners. In vivo ARFI images were acquired with a linear array placed on an exposed canine heart. The electrocardiogram (ECG) was also recorded. When co-registered with the ECG, ARFI displacement images of the heart reflect the expected myocardial stiffness changes during the cardiac cycle. A radiofrequency ablation was performed on the epicardial surface of the left ventricular free wall, creating a small lesion that did not vary in stiffness during a heartbeat, though continued to move with the rest of the heart. ARFI images showed a hemispherical, stiffer region at the ablation site whose displacement magnitude and temporal variation through the cardiac cycle were less than the surrounding untreated myocardium. Sequences with radiation force pulse amplitudes set to zero were acquired to measure potential cardiac motion artifacts within the ARFI images. The results show promise for real-time cardiac ARFI imaging.

show abstract

“…Hence, adjustments of burst intensity and its duration may be important factors when making comparisons between regions of differing depth. Yu et al recently characterized the parametric images of myocardial perfusion using low-MI intermittent triggered MCE [11]. These parametric and colorcoded images may be of utility for clinical determinations of the extent of the myocardial perfusion defect and the abnormal perfusion area.…”

Section: Discussionmentioning

confidence: 99%

Complete Bubble Destruction is Essential for Quantitative Assessment From the Replenishment Curve in Real-time Myocardial Contrast Echocardiography

et al. 2005

View full text Add to dashboard Cite

Background. Myocardial perfusion can be quantified using the replenishment curve of the myocardial opacification derived after transient high power ultrasound exposure (burst) in real-time myocardial contrast echocardiography (MCE). However, the effect of acoustic power of burst for bubble destruction may confound results. Thus, the goal of the present study was to examine the effect of burst intensity on the parameters of the replenishment curve. Results. The A-value remained constant with changes in the burst MI. Although the video intensity after the high intensity (0dB) burst was similar to that of the baseline, the video intensity after the low intensity (-11dB) burst was significantly higher than that of the baseline (anterior: 5.5±2.2 dB at baseline vs. 7.4±2.4 dB at -11dB burst; lateral: 5.9±2.5 dB at baseline vs. 9.3±3.2 dB at -11dB burst), which suggests that low MI burst results in incomplete bubble destruction. Furthermore, the -value increased as the burst MI decreased (anterior: 0.39±0.07 and 0.54±0.15; lateral: 0.27±0.05 and 0.39±0.12 in response to a burst MI of 0 and -11dB, respectively). Conclusions.The myocardial microbubble velocity ( -value) derived from the replenishment curve by using bubble destruction technique in real-time MCE is overestimated when bubble destruction is incomplete. (J Echocardiogr 2005; 3: 21-26)

show abstract

Incremental value of parametric quantitative assessment of myocardial perfusion by triggered Low-Power myocardial contrast echocardiography

Abstract: Myocardial parametric quantification demonstrates good agreement with SPECT and incremental agreement with VIS. Analysis strategies that incorporate MPQ demonstrate better agreement with SPECT than visual analysis alone.

Cited by 35 publications

References 19 publications

Real‐time perfusion adenosine stress echocardiography versus myocardial perfusion adenosine scintigraphy for the detection of myocardial ischaemia in patients with stable coronary artery disease

Real‐time perfusion adenosine stress echocardiography versus myocardial perfusion adenosine scintigraphy for the detection of myocardial ischaemia in patients with stable coronary artery disease

In Vivo Assessment of Myocardial Stiffness with Acoustic Radiation Force Impulse Imaging

Complete Bubble Destruction is Essential for Quantitative Assessment From the Replenishment Curve in Real-time Myocardial Contrast Echocardiography

Contact Info

Product

Resources

About