For each k, k 1 , k 2 , k 3 , k 4 ∈ N, we will denote by P k (k 1 , k 2), (k 3 , k 4) a tree of k + k 1 + k 2 + k 3 + k 4 + 1 vertices with the degree sequence (1, 1, 1, 1, 2, 2, 2,. .. , 2, 3, 3). Let α k 1 , β k 2 , σ k 3 , and δ k 4 be all four endpoints of the graph. Let the distance between both vertices of degree 3 be equal to k. A subset S of vertices of a graph P k (k 1 , k 2), (k 3 , k 4) is a dominating set of P k (k 1 , k 2), (k 3 , k 4) if every vertex in V P k (k 1 , k 2), (k 3 , k 4) − S is adjacent to some vertex in S. We investigate the dominating set of minimum cardinality of a graph P k (k 1 , k 2), (k 3 , k 4) to obtain the domination number of this graph. Finally, we determine an upper bound on the domination number of a graph P k (k 1 , k 2), (k 3 , k 4) .