Index of Suspicion * Case 1: Fatigue, Shortness of Breath, and Chest Pain in an Adolescent Boy * Case 2: Poor Feeding and Weight Gain, Tachypnea, and Vomiting in a Neonate * Case 3: Afebrile Seizures After a Bout of Diarrhea in a 2-year-old Girl

Scott, Claudeen; Srichai, Monvadi B.; Kulik, Dina M.; Mahmud, Farid H.; Olson, Christina A.; Paz, Julia

doi:10.1542/pir.32-3-123

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“…The analysis of the literature revealed 794 publications, 83 of which were included in this systematic review (Figure 1). Out of these, 68 permitted a detailed analysis of cases 4–8,11,17–78 while 15 publications, dealing with CwG and rotavirus infection, only reported prevalence and therefore did not allow a detailed analysis 10,48,79–91 . Although these latter 15 publications were not included in the systematic analysis, they were used to calculate the prevalence of CwG in rotavirus infection or the prevalence of rotavirus infection in patients with CwG (Figure 1).…”

Section: Resultsmentioning

confidence: 99%

Neurological complications of rotavirus infection in children: A systematic review and meta‐analysis

et al. 2023

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Rotavirus is a common cause of benign, self-limiting gastroenteritis in childhood. 1,2 Apart from dehydration and electrolyte imbalance, several neurological complications have been described in rotavirus infections in recent years, such as encephalitis, cerebellitis and a condition described as benign convulsions with mild gastroenteritis (CwG). [3][4][5][6] A direct viral pathomechanism has been postulated since the virus was first detected in the cerebrospinal fluid of a patient suffering from encephalitis in 1995 4 and in subsequent reports. 6,7 CwG was first described in 1982 by Morooka et al. in patients who presented with convulsions associated with mild gastroenteritis without fever or laboratory abnormalities. 3 The definition of CwG was further elaborated in 1992 by Komori et al. as convulsions in

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Section: Resultsmentioning

confidence: 99%