Eight medium magnitude (Mw 5.0-5.9) severely felt earthquakes, mostly at a shallower depth (<35 km), occurred in a short period of 7 months only, April-October, 2020, in Mizoram State, north-east region (NER) of India, and it created much panic in the state. The increasing population growth as well as rapid urbanization in Aizawl, the capital city of Mizoram, may be under severe threat for an impending large earthquake in the region. The NER, India, is jawed between two arcs, the Himalayan Arc collision zone to the north and the Indo-Burma (Myanmar) Arc subduction zone to the east, and witnessed two great earthquakes (Mw ≥ 8.0, 1897 and 1950) and a total of 25 large earthquakes (Mw ≥ 7.0) in the past since 1869. The 2020 sudden burst of seismic activity in Mizoram, along with a strong (Mw 6.7) earthquake in Manipur in 2016 and a medium magnitude (Mw 5.7) earthquake in 2017 in Tripura, adjacent to the Mizoram State, are critically examined to understand the ongoing seismotectonics and the precursor implications, if any. The 2016 Manipur earthquake is interpreted to be an intra-plate earthquake triggered by the transverse Kopili Fault by strike-slip motion. The 2017 Tripura earthquake is also interpreted to be typically an intra-plate strike-slip event in the eastern margin of the Bengal Basin. The seismic activity in Mizoram, on the other hand, is found to have occurred in the accretionary Indo-Burma Wedge, between the Churachandpur Mao Fault and Eastern Boundary Thrust. The centroid moment tensor solutions of the events suggest the dextral-slip motion of the wedge along the Indo-Burma Arc.A preliminary analysis of the Mizoram seismicity recognizes a precursor anomaly, a temporal variation of much higher seismic activity, for an impending large earthquake in the study area.