Objective: to analyze the association between the Clinical-Functional Vulnerability Index-20 and the dimensions of the functionality of the elderly person. Methods: cross-sectional study with 307 participants. The Clinical-Functional Vulnerability Index-20, Mental State Mini-Exam, Abbreviated Geriatric Depression, Timed Up and Go, Hearing Test and Whisper were used. Data were analyzed using descriptive statistics and 5% significance. Results: prevalence of fragility was 16.6% and fragility at risk was 43.0%, with higher proportions for the cognitive deficit, the risk for depression, high risk of falls, visual and auditory dysfunction. There was a significant association between fragility and mental status, depression, functional mobility (p<0.001), Snellen Signal Test (right eye p=0.015, left eye p=0.025) and Whisper Test (right and left ear p˂0.001). Conclusion: the early detection of fragility and its association with the dimensions of functionality are essential to care interventions, guaranteeing the autonomy and independence of the elderly person.