Indications &amp; Complications of Exchange Transfusion in A Tertiary Care Hospital

Saxena, Dr.Abhishek; Bairwa, Dr.A.L. Bairwa Dr.A.L.

doi:10.15373/22501991/mar2014/68

Cited by 3 publications

(4 citation statements)

References 8 publications

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“…Multiple exchange transfusion was required in 23.6% of our neonates, which is similar to the findings of Dikshit (22), but more than Abu-Ekteish et al (23). In our study, no etiologic factors were identified in 61 (41.2%) neonates, a rate reported previously as 17 -40% (16,(24)(25)(26)(27) and ABO incompatibility was observed in 54 (36.5%) neonates, which is similar to other studies (28)(29)(30). Rh incompatibility alone or concomitant with ABO incompatibility was observed in 15 (10.1%) and 3 (2.0%) neonates, respectively.…”

Section: Discussionsupporting

confidence: 90%

Complications of Exchange Transfusion in Hospitalized Neonates in Two Neonatal Centers in Hamadan, A Five-Year Experience

et al. 2015

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Background: Exchange transfusion is commonly used in newborns for immediate treatment of severe hyperbilirubinemia to prevent bilirubin encephalopathy and kernicterus. Objectives: This study aimed to determine etiology and complications in newborns who received exchange transfusion for severe hyperbilirubinemia over the last five years. Patients and Methods: A retrospective study was performed on 28 days old infants who received exchange transfusion due to severe hyperbilirubinemia for a period of five years (from October 1st, 2006 through September 30th, 2011) in two neonatal units at Besat and Fatemieh hospitals in Hamadan, Iran. All data about patients' demographic characteristics, causes of hyperbilirubinemia, frequency, and complications of exchange transfusion were collected from medical records and analyzed using SPSS Version 12.0). Results: Exchange transfusion was performed in 148 neonates. Eighteen patients (12.2%) received exchange transfusion twice and seventeen patients (11.4%) three times or more. Among 118 neonates 80 (54.9%) were female and the mean gestational age and birth weight were 37.2 ± 2.5 weeks and 2847 ± 699 grams, respectively. The mean maximum total serum bilirubin levels were 27. 7.6 ± 7.28 mg/dL. Hemolytic disease was found in 72 (48.6%) of newborns. The most common cause of hemolysis was ABO incompatibility in 54 (36.5%). The etiologic factors were unidentified in 61 (41.2%) neonates. Complications occurred in 57 (38.5%) neonates and the most common complications were thrombocytopenia in 26 (17.6%) and hypocalcaemia in 17 (11.5%) neonates. Mortality was found in one (0.7%) neonate. Conclusions: The etiology of exchange transfusion was unidentified in most cases; however, ABO incompatibility was the most prevalent cause of hyperbilirubinemia. Complications were common after exchange transfusion and should be considered carefully.

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Section: Discussionsupporting

confidence: 90%

Complications of Exchange Transfusion in Hospitalized Neonates in Two Neonatal Centers in Hamadan, A Five-Year Experience

et al. 2015

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“…In newborns with jaundice, the frequently occurring indications of exchange transfusion, reported by a study were ABO incompatibility (25%), Rh incompatibility (41.67%) and in (33.33%) cause was unknown. 4 Another study noted indications of exchange transfusion to be ABO incompatibility in 30.0% neonates, Rh incompatibility 13.3%, septicaemia 6.6% while in 50% cases, no identifiable cause was found. 5 For hyperbilirubinemia in newborns, ABO incompatibility (25%) was found to be the most frequent causative factor for which exchange transfusion was executed whereas Rh incompatibility (21.3%) was after that.…”

Section: Discussionmentioning

confidence: 98%

“…The minimum sample size of 113 neonates was calculated considering frequency of ABO incompatibility as 25% with confidence level 95% and margin of error as 8%. 4 Sample Selection: For this study, we enrolled 131 neonates adopting non-probability consecutive sampling technique. Inclusion criteria were neonates of either gender up to 28 days of age, suffering from jaundice.…”

Section: Sample Sizementioning

confidence: 99%

“…2,3 Literature shows that ABO incompatibility (25%), Rh incompatibility 10 (41.7%) and unidentified causes (33.3%) are the most frequently noted conditions for exchange transfusion in the jaundiced newborns. 4 Another study revealed that ABO compatibility (30.0%), Rh compatibility (13.3%), septicemia (6.6%) and unidentified causes (50%) were the commonest indications for exchange transfusion. 5 It was described in a study that the most frequently observed causative factor of neonatal hyperbilirubinemia where exchange transfusion was indicated and performed were ABO incompatibility spotted in 25% jaundiced newborns followed by Rh incompatibility in 21.3%.…”

Section: Introductionmentioning

confidence: 99%

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Common Indications of Exchange Transfusion in Neonates with Jaundice Presenting to a Tertiary Care Health Facility

Ashfaq¹,

Bai²,

Bader-U-³

et al. 2023

PJMHS

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Objective: To determine the frequency of common indications of exchange transfusion in neonates with jaundice presenting to a tertiary care health facility. Study Design: A descriptive cross-sectional study. Place and Duration: Department of Paediatrics, National Institute of Child Health, Karachi Pakistan, from January 2022 to June 2022. Methodology: All neonates up to 28 days of either gender presenting with jaundice were included. Details about gender, ethnicity, blood group, feeding practices and indications of exchange transfusion were noted. Results: The mean age of the patients was 10.71±9.68 days. There were 66 (50.4%) males and 65 (49.6%) females. The Mean weight and gestational age were found to be 3.39±0.37 kg and 39.34±1.07 weeks respectively. Feeding practice among majority (n=78, 59.5%) of the mother was mixed (n=78, 59.5%). ABO incompatibility was observed in 31 (23.7%), Rh incompatibility in 24 (18.3%) and unidentified cause in 11 (8.4%) neonates. Practical Implications: For hyperbilirubinemia in neonates, ABO incompatibility was found to be the most frequent causative factor behind exchange transfusion. Conclusion: ABO incompatibility was found to be the most common indications of exchange transfusion followed by Rh incompatibility in neonates with jaundice presenting to tertiary care facility. Keywords: ABO incompatibility, exchange transfusion, jaundice, Rh incompatibility, neonates.

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Exchange Transfusion in Neonates: An Experience From a Tertiary Care Center in North India

Naranje¹,

Singh²,

Panghal³

et al. 2019

IJCH

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Indications & Complications of Exchange Transfusion in A Tertiary Care Hospital

Cited by 3 publications

References 8 publications

Complications of Exchange Transfusion in Hospitalized Neonates in Two Neonatal Centers in Hamadan, A Five-Year Experience

Complications of Exchange Transfusion in Hospitalized Neonates in Two Neonatal Centers in Hamadan, A Five-Year Experience

Common Indications of Exchange Transfusion in Neonates with Jaundice Presenting to a Tertiary Care Health Facility

Exchange Transfusion in Neonates: An Experience From a Tertiary Care Center in North India

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