Indications and Results of Transanal Endoscopic Microsurgery in the Treatment of Rectal Tumours in a Consecutive Series of 52 Patients

Márquez, Manuel; Duarte, Ángel Reina; Gil, Francisco Rubio; Lozano, Ricardo Belda; García, A.; Sierra, Isabel Blesa

doi:10.1016/j.cireng.2011.04.006

Cited by 6 publications

(1 citation statement)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…So the full-thickness and en-bloc excision is achieved with adequate resection margins around the lesion [21]. Sutures are required in anterior tumours which are lying above the peritoneal reflection in order to prevent rectal perforation [20][21][22]. Tumours at 16 to 20 cm from the anal verge were included in some studies [22,23].…”

Section: Discussionmentioning

confidence: 99%

Surgical Management of Large Villous Tumours

Toughraï¹,

Mellouki²,

Kamaoui³

et al. 2013

JCR

View full text Add to dashboard Cite

Abstract:Villous tumours of digestive tract are rare and pre malignant lesions. Their discovery is, usually, fortuitous during an endoscopic examination. The removal of villous tumours must be complete, because of their recurrence and degeneration potential. Large villous tumors are still a limitation for endoscopic removal and need a surgical management. High morbidity and mortality rate and functional disorders of radical surgery have led to an increasing interest in many other procedures which can expose to recurrence risk especially in rectal localization. We review the literature and report our experience in managing two cases of large villous tumours in two different localizations.

show abstract

Section: Discussionmentioning

confidence: 99%

Surgical Management of Large Villous Tumours

Toughraï¹,

Mellouki²,

Kamaoui³

et al. 2013

JCR

View full text Add to dashboard Cite

show abstract

Risk of recurrence after local resection of T1 rectal cancer: a meta-analysis with meta-regression

et al. 2022

View full text Add to dashboard Cite

Background T1 rectal cancer (RC) patients are increasingly being treated by local resection alone but uniform surveillance strategies thereafter are lacking. To determine whether different local resection techniques influence the risk of recurrence and cancer-related mortality, a meta-analysis was performed. Methods A systematic search was conducted for T1RC patients treated with local surgical resection. The primary outcome was the risk of RC recurrence and RC-related mortality. Pooled estimates were calculated using mixed-effect logistic regression. We also systematically searched and evaluated endoscopically treated T1RC patients in a similar manner. Results In 2585 unique T1RC patients (86 studies) undergoing local surgical resection, the overall pooled cumulative incidence of recurrence was 9.1% (302 events, 95% CI 7.3–11.4%; I2 = 68.3%). In meta-regression, the recurrence risk was associated with histological risk status (p < 0.005; low-risk 6.6%, 95% CI 4.4–9.7% vs. high-risk 28.2%, 95% CI 19–39.7%) and local surgical resection technique (p < 0.005; TEM/TAMIS 7.7%, 95% CI 5.3–11.0% vs. other local surgical excisions 10.8%, 95% CI 6.7–16.8%). In 641 unique T1RC patients treated with flexible endoscopic excision (16 studies), the risk of recurrence (7.7%, 95% CI 5.2–11.2%), cancer-related mortality (2.3%, 95% CI 1.1–4.9), and cancer-related mortality among patients with recurrence (30.0%, 95% CI 14.7–49.4%) were comparable to outcomes after TEM/TAMIS (risk of recurrence 7.7%, 95% CI 5.3–11.0%, cancer-related mortality 2.8%, 95% CI 1.2–6.2% and among patients with recurrence 35.6%, 95% CI 21.9–51.2%). Conclusions Patients with T1 rectal cancer may have a significantly lower recurrence risk after TEM/TAMIS compared to other local surgical resection techniques. After TEM/TAMIS and endoscopic resection the recurrence risk, cancer-related mortality and cancer-related mortality among patients with recurrence were comparable. Recurrence was mainly dependent on histological risk status. Graphical abstract

show abstract