“…Several primary or secondary disorders of the AV conduction system are capable of inducing 3AVB, but usually, the cause is unknown (Willis, 2018). However, many underlying causes for 3AVB in canines have been cited including degeneration and fibrosis of the AV conduction system (Kaneshige et al, 2007), isolated congenital AV block, inherited heart defects, adrenal insufficiency (Patterson et al, 1961), myocarditis, cardiomyopathy, infections, myocardial infarction, hyper-hypokalemia, drugs intoxication (digoxin and calcium channel blockers), cardiac neoplasia, immune-mediated and inflammatory diseases (myasthenia gravis, lupus erythematosus), trauma, inflammation and systemic disorders (Willis, 2018;Santilli et al, 2019) and pancreatitis (Oron et al, 2015).…”