Indications for radioisotope bone scanning in staging of cervical cancer

Hirnle, P; Mittmann, K.-P.; Schmidt, Bernard; Pfeiffer, K. H.

doi:10.1007/bf02389585

Cited by 4 publications

(2 citation statements)

References 7 publications

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“…In addition, a bone scan is a useful diagnostic tool for the detection of distant metastases and to differentiate the isolated distant metastasis from diffuse metastasis [ 77 ]. Patients with stage I and stage II carcinoma of the cervix may not require a bone scan [ 78 79 ]. Currently, there is no specific widely accepted guideline for the treatment of patients with bone involvement.…”

Section: Patients With Hematogenous Metastasismentioning

confidence: 99%

Advances in diagnosis and treatment of metastatic cervical cancer

2016

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Cervical cancer is one of the most common cancers in women worldwide. The outcome of patients with metastatic cervical cancer is poor. We reviewed the relevant literature concerning the treatment and diagnosis of metastatic cervical cancer. There are two types of metastasis related to different treatments and survival rates: hematogenous metastasis and lymphatic metastasis. Patients with hematogenous metastasis have a higher risk of death than those with lymphatic metastasis. In terms of diagnosis, fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) and PET-computed tomography are effective tools for the evaluation of distant metastasis. Concurrent chemoradiotherapy and subsequent chemotherapy are well-tolerated and efficient for lymphatic metastasis. As for lung metastasis, chemotherapy and/or surgery are valuable treatments for resistant, recurrent metastatic cervical cancer and chemoradiotherapy may be the optimal choice for stage IVB cervical cancer. Chemotherapy and bone irradiation are promising for bone metastasis. A better survival is achieved with multimodal therapy. Craniotomy or stereotactic radiosurgery is an optimal choice combined with radiotherapy for solitary brain metastases. Chemotherapy and palliative brain radiation may be considered for multiple brain metastases and other organ metastases.

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Section: Patients With Hematogenous Metastasismentioning

confidence: 99%

Advances in diagnosis and treatment of metastatic cervical cancer

2016

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“…In the studies of Blythe et al 8 only one out of 55 cases presented with pathologic fracture. Osseous metastasis is rare in patients of carcinoma cervix So X-ray is not recommended routinely and is done only in symptomatic patients 12 . The atypical location of pain should alert the physician to suspect distant metastasis.…”

Section: Discussionmentioning

confidence: 99%

Humeral Metastasis in a case of Squamous Cell Carcinoma - a Case Report

Baviskar¹,

Pruthi²,

Dongre³

et al. 2011

Internet Journal of Medical Update - EJOURNAL

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A rare case of squamous cell carcinoma with metastasis to distal acral skeleton -humerus within two months of diagnosis of the primary is being reported. The metastasis to the bones from carcinoma cervix is uncommon especially in the distal appendicular skeleton. A 47 years female came with spontaneous fracture of right humerus shaft. The tissue from fracture site revealed metastasis of squamous cell carcinoma. X-Ray lung and USG abdomen did not show any organ involvement. She was diagnosed as squamous cell carcinoma cervix stage III B two months before and put on radiotherapy and chemotherapy. This is one of the few documented cases of metastasis to humerus without involvement of lung liver or brain within two months of diagnosis of the primary.

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Bone metastasis from cervical cancer

Ratanatharathorn

Powers

Steverson

et al. 1994

Cancer

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Background. This retrospective analysis examines the frequency, distribution, and the pattern of disease progression of bone metastasis in patients treated for cervical cancer and the use and results of palliative intent radiation therapy. Methods. Charts, films, and other available records were reviewed for the 41 patients with bone metastasis of the 496 patients with invasive cervical cancer treated at the Gershenson Radiation Oncology Center, Detroit, Michigan, from 1980 through 1989. Results. Several patterns of bone metastasis were observed: (1) direct extension into bone from the parametrial extensions of the primary or recurrent pelvic tumor, (2) direct extension into bone from parenchymal metastasis to distant lymph nodes or lung, (3) regional hematogenous metastasis compatible with Batson's venous plexus distribution, and (4) systemic hematogenous metastasis to distant bones. Eighty percent of the patients were irradiated, and of those, 70% experienced pain relief. Conclusions. Bone metastasis in patients with cervical cancer is an infrequent but significant occurrence with associated severe dysfunction, other signs of local and distant failure, and short life expectancy. Radiation therapy provides moderate palliation for treatable patients.

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Indications for radioisotope bone scanning in staging of cervical cancer

Cited by 4 publications

References 7 publications

Advances in diagnosis and treatment of metastatic cervical cancer

Advances in diagnosis and treatment of metastatic cervical cancer

Humeral Metastasis in a case of Squamous Cell Carcinoma - a Case Report

Bone metastasis from cervical cancer

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