Indications for referral and assessment in adultliver transplantation: a clinical guideline

Devlin, John; O’Grady, John

doi:10.1136/gut.45.2008.vi1

Cited by 84 publications

(33 citation statements)

References 197 publications

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“…195 Malignant invasion of the venous drainage, which is strongly associated with tumour recurrence following OLT (see below), is also considered a contraindication. 196 However, while macrovascular invasion may be detected on preoperative imaging, microvascular infiltration is a histopathological diagnosis that, in the absence of preoperative biopsy, cannot be made prior to hepatectomy. 197 Extrahepatic metastases also contraindicate OLT.…”

Section: Indicationsmentioning

confidence: 99%

See 1 more Smart Citation

Surveillance of cirrhosis for hepatocellular carcinoma: systematic review and economic analysis

Coon¹,

Rogers²,

Hewson³

et al. 2007

Health Technol Assess

151

108

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Section: Indicationsmentioning

confidence: 99%

“…197 Extrahepatic metastases also contraindicate OLT. 196 NHS guidance stipulates that patients should be listed for OLT "only if the clinician feels that they have a greater than 50% probability of survival at Aims and background 5 years after transplantation with a quality of life that is acceptable to the patient. "…”

Section: Indicationsmentioning

confidence: 99%

Surveillance of cirrhosis for hepatocellular carcinoma: systematic review and economic analysis

Coon¹,

Rogers²,

Hewson³

et al. 2007

Health Technol Assess

151

108

View full text Add to dashboard Cite

show abstract

“…Others in this category are patients who have end-stage cardiac, hepatic or pulmonary failure. The cut-off marks selected here are adapted from the transplant literature [42][43][44][45] and typically represent a baseline death rate higher than 50% within the next 1 to 2 years. Given that transplantation is unlikely during a pandemic, combined with the cumulative risk of death from their acute critical illness, these patients again fall into a category where considerable resources would have to be expended with a low probability of long-term survival.…”

Section: Figmentioning

confidence: 99%

Development of a triage protocol for critical care during an influenza pandemic

Christian¹,

Hawryluck²,

Wax³

et al. 2006

Canadian Medical Association Journal

335

344

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“…Early indication to LTx made it possible to patients to reach survival rate above 70% in five years, and also reduced the treatment costs. Moreover, it is important to highlight that the patients who use medication treatment for the disease at final stage present mortality of 70% per year (13,14) . These data caused that the search for the surgical procedure for the hepatic disease solution significantly increased.…”

Section: Introductionmentioning

confidence: 99%

Capacidade funcional e força muscular respiratória de candidatos ao transplante hepático

Pereira

Figueredo

Galant

et al. 2011

Rev Bras Med Esporte

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Introduction: Chronic liver disease results in large functional impact, causing loss of muscle mass and function with consequent reduction of functional capacity. Objective: To evaluate and compare the respiratory muscle strength and functional capacity of candidates for liver transplantation who are under Class B or C according to Child Pugh Score and to correlate these variables within each group. Methods -Cross-sectional study with a convenience sample of 35 patients divided into two groups based on the score obtained in the Child Pugh Score B (19 patients) and Child Pugh Score C (16 patients). All subjects were evaluated in a single moment, and the maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) as well as the distance walked during the 6-minute walk test (6MWT) were measured. Results: Individuals classified with Child Pugh Score B showed higher values in the MIP (-86.05 vs. 23.89 -57.94 14.14), p = 0.001, in MEP (84.16 vs. 28.26 72.00 16 1994), p = 0.142, and the distance walked in 6MWT (473.63 vs 376.13 39.00 55.276), p = 0.001. We also found a positive correlation between the values of MIP and distance walked during 6MWT in group B of the Child Pugh Score, r = 0.64 and p = 0.003. Conclusion: The progress of liver disease contributes to the onset of several complications, which together appear to contribute to the reduction of functional capacity of individuals. In our study this was evidenced by the worse performance of Child Pugh score C group. This may suggest that the wait for liver transplantation (LTx) can worsen the functional capacity of these individuals.

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Indications for referral and assessment in adultliver transplantation: a clinical guideline

Cited by 84 publications

References 197 publications

Surveillance of cirrhosis for hepatocellular carcinoma: systematic review and economic analysis

Surveillance of cirrhosis for hepatocellular carcinoma: systematic review and economic analysis

Development of a triage protocol for critical care during an influenza pandemic

Capacidade funcional e força muscular respiratória de candidatos ao transplante hepático

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