Indices for the assessment of environmental pollution of the Baltic Sea coasts: Integrated assessment of a multi-biomarker approach

Broeg, Katja; Lehtonen, Kari K.

doi:10.1016/j.marpolbul.2006.02.004

Cited by 282 publications

(153 citation statements)

References 35 publications

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“…Since the IBR value is directly dependent on the number of biomarkers in the set, the obtained IBR value must be divided by the number (N = 6) of biomarkers used and termed as IBR/n (Broeg and Lehtonen, 2006). Biomarker were ordered according to their level of biological complexity from genotoxicity (COMET) to population fitness (SOS), with subcellular (LMS), cellular (MDA), and tissue (CAT, SOD) biomarkers in between.…”

Section: Integrative Biomarker Indicesmentioning

confidence: 99%

Temporal and spatial distribution of semicarbazide in western Laizhou Bay

Tian

Song

et al. 2016

Marine Pollution Bulletin

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a b s t r a c t a r t i c l e i n f oArticle history: Received 9 January 2016 Received in revised form 26 July 2016 Accepted 29 July 2016 Available online xxxx An integrative biomarker approach was employed to evaluate the environmental quality of the north coast of Shandong Peninsula along the southern Bohai Sea of China, where pollution is an imminent threat due to rapid urbanization and industrialization. A battery of biomarkers and the metal bioaccumulation in tissues of native oyster Crassostrea gigas were measured under field conditions. Integrative biomarker index (IBR) and metal body burden were calculated to differentiate the pollution status of seven sampling sites. According to our results, Xinzhuang (XZ) site was the most severely contaminated, with the highest IBR value of 3.58, while the lowest IBR value (0.04) was obtained at Penglai (PL). Such an integrated biomarker approach was proved as a useful method for environmental quality assessment in the study area.

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Section: Integrative Biomarker Indicesmentioning

confidence: 99%

Temporal and spatial distribution of semicarbazide in western Laizhou Bay

Tian

Song

et al. 2016

Marine Pollution Bulletin

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“…In the last decades, environmental genotoxicity in coastal areas of the Baltic and the North Seas was assessed in the number of studies (Al-Sabti and Hardig, 1990;Bresler et al, 1999;Baršienė et al, 2000, Thiriot-Quiévreux and Wolowicz, 2001Bombail et al, 2001;Frenzilli et al, 2004;Schiedek et al, 2006;Kopecka et al, 2006;Broeg and Lehtonen, 2006;Lehtonen et al, 2006;Stachnik and Wolowicz, 2007;Köhler and Ellesat, 2008). However, there is a lack of information on genotoxic and cytotoxic effects in the offshore areas of the Baltic and the North Seas.…”

Section: Introductionmentioning

confidence: 99%

Environmental genotoxicity and cytotoxicity in the offshore zones of the Baltic and the North Seas

Rybakovas

Baršienė

Lang

2009

Marine Environmental Research

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Please cite this article as: Rybakovas, A., Baršienė, J., Lang, T., Environmental genotoxicity and cytotoxicity in the offshore zones of the Baltic and North Seas, Marine Environmental Research (2009Research ( ), doi: 10.1016Research ( /j.marenvres. 2009 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. ACCEPTED MANUSCRIPT AbstractMicronuclei (MN), nuclear buds (NB) and fragmented-apoptotic cells (FA) were analyzed in mature peripheral blood and immature cephalic kidney erythrocytes of flounder (Platichthys flesus), dab (Limanda limanda) and cod (Gadus morhua) from 12 offshore sites in the Baltic Sea (479 specimens) and 11 sites in the North Sea (291 specimens), which were collected during three research vessel cruises in December 2002 and in September 2004. The highest levels of environmental genotoxicity (frequencies of MN up to 0.5 ‰, NB -up to 0.75 ‰) and cytotoxicity (FA -up to 0.53 ‰) were observed in flatfishes from areas close to oil and gas platforms in the North Sea and in zones related to the extensive shipping and potentially influenced by contamination from large European Rivers (Elbe, Vistula, Oder). In dab from the offshore zones of the North Sea, the levels of nuclear abnormalities were higher as compared to those in dab from the Baltic Sea. Responses in immature kidney erythrocytes were higher than in mature erythrocytes from peripheral blood. MN frequency lower than 0.05 ‰ (the Baltic Sea) and lower than 0.1 ‰ (the North Sea) could be suspected as a reference level in the peripheral blood erythrocytes of flatfish.Keywords: Genotoxicity; Cytotoxicity; Micronuclei; Nuclear abnormalities; Erythrocytes; Baltic Sea; North Sea. ACCEPTED MANUSCRIPT 2 IntroductionSurrounded by European countries, the Baltic and the North Seas are constantly exposed to anthropogenic pressure. With pollution from land-based discharges, coastal industries, municipal outflows, agricultural activities, oil and gas industry (drilling and transportation) and transport activities, thousands of chemicals are entering the marine environment. A large proportion of these compounds are potentially toxic, genotoxic and carcinogenic to aquatic organisms (Jha, 2004(Jha, , 2008. The interaction of genotoxic contaminants with DNA causes various genetic disturbances, which often are irreversible and can be transmitted to the next generations (Depledge and Fossi, 1994;Dixon et al., 1999;Jha, 2004). The analysis of environmental genotoxicity provides early warning signs of adverse long-term effects of contamination. A number of biomarkers have been applied for assessment of environmental genotoxicity and the micronuclei (MN) test,...

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“…The use of indices to summarize biomarker responses for the evaluation of contaminant-induced stress has been increasingly employed and this approach is useful from an environmental management perspective (Beliaeff and Burgeot 2002;Broeg and Lehtonen 2006;Hagger et al 2009). In this study, the IBRv2 index based on the reference deviation concept was applied to integrate biomarker responses into a stress index (Sanchez et al 2013).…”

Section: Discussionmentioning

confidence: 99%