Indirect and direct approaches in the synthesis of a new mono-6-O-benzyl methylated γ-cyclodextrin as chiral selector for enantioselective gas chromatography

Insertion of a Single‐Molecule Magnet inside a Ferromagnetic Lattice Based on a 3D Bimetallic Oxalate Network: Towards Molecular Analogues of Permanent Magnets

“…Herein, new trifluoromethanesulfonic salts of permethylated mono‐6‐deoxy‐6‐(pyridin‐1‐ium)‐α‐cyclodextrin ( 4 a ), mono‐6‐deoxy‐6‐(pyridin‐1‐ium)‐β‐cyclodextrin ( 4 b ), mono‐6‐deoxy‐6‐(1‐vinyl‐1 H ‐imidazol‐3‐ium)‐α‐cyclodextrin ( 5 a ), and mono‐6‐deoxy‐6‐(1‐vinyl‐1 H ‐imidazol‐3‐ium)‐β‐cyclodextrin ( 5 b ; Scheme ) were synthesized by a protection/deprotection strategy 7. 11j, 30 This strategy deals with the use of chemo‐ and/or regioselective reactions from native CDs including four main steps: selective protection of one C‐6 hydroxyl group, transformation of the remaining ones, deprotection, and finally, suitable functionalization afforded by nucleophilic displacement.…”

Chiral Separations: Fundamental Review 2010

“…A new mono-6-O-benzyl methylated γ-cyclodextrin CSP was synthesized, and preliminary enantioselective GC applications were reported (229). An acyclic maltooctaose derivative was used as a CSP for enantioselective GC and was compared to its cyclic counterpart (230).…”

The Use of Cyclodextrins Nanoparticles for Oral Delivery

“…Nanoparticles can also be made from degradable materials to prevent the gradual build-up of nanoparticles in the human body, which is not a desirable goal [1][2][3]7]. CD Surfactants [11,12,16] CD Conjugates ~ [13,14] Polyrotaxanes [17] Chitosan [18][19][20] Micelle Swelling [21,22] Nanoclay [25] Copolymer (CD) [26] Star Copolymer [27,28] …”

“…Because of the structure of a glucose molecule the cyclic structure conforms into a tapered cylindrical shape containing a hydrophobic pocket inside the cylinder and outside of the cylinder become hydrophilic faces. It is possible to functionalise the cyclodextrins to varying degrees, and also the ability to monosubstitute a functionalised glucose onto a nonfunctionalised cyclodextrin [12]. Cyclodextrins are traditionally and most easily made via an enzyme catalysed reaction, using starch as the starting material it is broken down by an enzyme in the glucosyltransferase family to produce the cyclic compound.…”

“…Cyclodextrins are traditionally and most easily made via an enzyme catalysed reaction, using starch as the starting material it is broken down by an enzyme in the glucosyltransferase family to produce the cyclic compound. More complex methods are required when creating more complex cyclodextrins [12]. There are many ways to administer a medicine to a patient.…”