Indium trichloride–catalyzed synthesis of some novel 2,2′‐(N,N′‐diarylamino)‐ 4,4′‐diaryl‐5,5′‐arylidenebisthiazoles and their insecticidal activity

Abstract

A series of novel 2, (IR, PMR and Mass). The synthesized compounds were also evaluated for their insecticidal activity against Helicoverpa armigera and gave promising results.

Eco-friendly Solventless Synthesis of 5-Indolylpyrimido[4,5-d]pyrimidinones and Their Antimicrobial Activity

“…As an extension to our endeavor towards the synthesis of bioactive molecules [23][24][25] utilizing green methodologies we now wish to report the synthesis of 5-indolylpyrimido[4,5-d]pyrimidinones by grindstone technology in which the carbon atoms carrying the oxo, thio and NH sites can be utilized as centers to obtain various derivatives for the potential use in combinatorial chemistry. 26 5-Indolylpyrimido[4,5-d]pyrimidinones were classically prepared by 'one pot' multi-component reaction in which the three reactants were refluxed in ethanol in acidic medium.…”

A “One Pot,” Environmentally Friendly, Multicomponent Synthesis of 2‐Amino‐5‐cyano‐4‐[(2‐aryl)‐1H‐indol‐3‐yl]‐6‐hydroxypyrimidines and Their Antimicrobial Activity

“…In continuation to our earlier research work on green chemistry , we are reporting herein, for the first time, the synthesis of titled compounds by three‐component condensation of 3‐formylindole, ethylcyanoacetate, and guanidine hydrochloride with NaOH in “one pot” by conventional heating and eco‐friendly methods (microwave irradiation and grindstone technology) (Scheme ) and also reporting their antibacterial activity against gram positive ( Pseudomonas aeruginosa ) and gram negative bacteria ( Escherichia coli ) and antifungal activity against fungi ( Rhizopus stolonifer , Aspergillus flavus , Fusarium oxysporum ), and all the synthesized compounds further were investigated to antimicrobial activity against nine pathogenic microorganisms including eight bacterial species and one fungi with different antibiotic.…”

Synthesis, Transformation of 3-[(4-Arylthiazol-2-yl)(p-tolyl)amino]propanoic Acids, Bis(thiazol-5-yl)phenyl-, Bis(thiazol-5-yl)methane Derivatives, and Their Antimicrobial Activity

“…24 Furthermore, arylidenebis(thiazoles) show promising results as insecticidal agents. 25 Taking all this into account, the task of the present work was to synthesize novel variously functionalized thiazole derivatives and to evaluate their antimicrobial activity.…”