Individual Quality of Life in Chronic Kidney Disease

Abstract

Background and objectives: Novel individualized quality-of-life (IQOL) measures permit patients with chronic kidney disease (CKD) to nominate unique areas of their lives that contribute to their well-being. This study assessed for differences in domains nominated by patients with CKD. We also examined the strength of association between (1) multidimensional health-related quality-of-life measures and IQOL and (2) Results: Patients with CKD nominated many domains on the SEIQOL-DW, but family and health were the most common for all groups. Kidney disease was listed more frequently by peritoneal dialysis compared with hemodialysis patients or patients with CKD (31 versus 14 versus 5%, respectively). There were no significant differences in SEIQOL-DW scores between subgroups. SEIQOL-DW scores correlated with mental well-being and inversely correlated with chronic stress and depression.Conclusions: Patients with advanced CKD demonstrate compromised quality-of-life scores comparable to dialysis patients. IQOL measures provide unique information that may help guide interventions that are better tailored to address patients' concerns about their well-being. These findings also suggest that renal clinics should have staff available to address psychosocial aspects of patient well-being.

Numeracy Skills in CKD

“…As part of a previously described (24,25) larger prospective cohort study investigating memory, sleep, and quality of life in adult, Englishspeaking patients with advanced CKD, we approached patients during their routine CKD clinic visit, dialysis clinic visit, or their initial evaluation at a kidney transplantation clinic between March 2004 and October 2007. Exclusion criteria included extremes of age and active, severe medical or psychiatric illness as has been previously described (24,25).…”

Self-Management Program for People with Chronic Kidney Disease in Vietnam: A Pragmatic Randomised Controlled Trial

“…Health-related quality of life is subjective and is influenced by a person's beliefs, which change over time (Abdel-Kader et al, 2009;Howard, Mattacola, Howell, & Lattermann, 2011;Schwartz, Andresen, Nosek, & Krahn, 2007). This change is termed response shift (Fayers & Machin, 2016;Howard et al, 2011;Schwartz et al, 2007), and this occurs when an individual with a chronic disease adapts to their illness and learns to cope with their altered health state.…”

Age and Dialysis Adequacy in Maintenance Hemodialysis Patients

“…From the beginning of the dialysis era, the issue of optimal dialysis dose and frequency has been a central topic in the delivery of dialysis treatment. Because among patients with end-stage renal disease who are treated with HD, solute clearance during dialysis is determinant of mortality and low urea reduction ratios during dialysis are associated with increased odds ratios for death [13][14][15][16][17][18]. Many patients enter for regular HD, are older and they are prone to some complications of hemodialysis.…”

“…Many patients enter for regular HD, are older and they are prone to some complications of hemodialysis. Patient's age by itself affects the HD procedure and may be complicated by the resultant problems, one of which is dialysis efficiency [12][13][14][15][16][17][18][19][20]. Low dialysis efficiency may influence nutrition and facilitate insidious malnutrition [21][22][23][24][25].…”

“…Low dialysis efficiency may influence nutrition and facilitate insidious malnutrition [21][22][23][24][25]. The urea reduction rate is a function of the clearance of urea from the blood by the dialyzer, the length of the individual dialysis treatment, and the volume of distribution of urea in a particular patient [15][16][17][18][19][20]. Therefore, the urea reduction rate (URR) is a quantitative measurement of an individual patient's urea clearance during a single HD treatment and can be used as a proxy for the adequacy of solute clearance during a treatment [20][21][22][23][24][25][26].…”