Individual red blood cell (RBC) transit analysis through sized micropores of oligopore filters : Application to RBC subpopulations

Guillet, R.; Vetter, J.; Koutsouris, D.; Beuzard, Yves; Boynard, M.

doi:10.1016/1359-0189(91)90336-g

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2004

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“…red cells pass through filtering holes of uniform size under a given pressure, determines deformability of red cells by measuring the rate of filtered red cells. It mimics the deformation in the natural capillary and deformability can be measured by allowing individual red cells to pass through holes with different size [19][20][21]. Therefore it is more practical for clinical application.…”

Section: Introductionmentioning

confidence: 99%

Research on a method for automated measurement of red cell deformability

Yu¹,

Liu²,

Zhang³

2004

Meas. Sci. Technol.

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Several existing laser diffractometric methods of measuring red cell deformability are analysed and their disadvantages are identified. By establishing the mathematical model of the diffraction image of a red cell group, a new method is presented—measurement of the greyscale of diffraction images. With numerous experiments, this method allows us to statistically obtain the deformation indices of both normal and abnormal red cells, as well as the composition of red cells in the blood and the characteristic values of specific red cells. It is demonstrated that abundant information including characteristics of red cells can be obtained with this method. This method is expected to be promising in both blood disease research and clinical application.

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Section: Introductionmentioning

confidence: 99%