Individual versus standard quality of life assessment in a phase II clinical trial in mesothelioma patients: Feasibility and responsiveness to clinical changes

Extrapleural pneumonectomy for early stage malignant pleural mesothelioma: A harmful procedure

“…Ambrogi and colleagues reported a global QoL amelioration, in particular when focusing on disease-related pain and physical role at 3 months after surgery; their results worsened after 12 months [15]. Similar conclusions were noted by other authors [16,17]. The difference between these studies and the present one may be due to the different composition of the series.…”

“…Some authors in the recent past published about QoL after EPP within multimodality treatment for MPM [15][16][17]. Ambrogi and colleagues reported a global QoL amelioration, in particular when focusing on disease-related pain and physical role at 3 months after surgery; their results worsened after 12 months [15].…”

Extrapleural Pneumonectomy After Induction Chemotherapy: Perioperative Outcome in 251 Mesothelioma Patients From Three High-Volume Institutions

“…Recent reported trials for trimodality therapy including EPP show that mortality can be reduced to 0% to 8.2% in experienced centers [4], in contrast to the reported 12.5% mortality of the MARS, trial representing one of the highest mortality rates for EPP in the current literature [2]. Morbidity after EPP stays high (22% to 82%) but seems to be manageable in terms of improvement of quality of life for all values 3 months postoperatively [5][6][7].…”

Systematic Review On Pleurectomy/Decortication In The Multimodality Treatment of Malignant Pleural Mesothelioma

“…Analyzing the postoperative quality of life (QoL) after P/D or EPP, we found only four studies objectively reporting on QoL after radical treatment of MPM [18,23,[33][34]. Generally patients who had EPP had a worse QoL than those following P/D.…”