2004
DOI: 10.1016/s0142-9612(03)00516-7
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Individualised, micro CT-based finite element modelling as a tool for biomechanical analysis related to tissue engineering of bone

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Cited by 162 publications
(116 citation statements)
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“…Computational methods have been widely used to predict bone failure during disease and after prosthetic implantation, but for many years these methods assumed that the material behaviour was homogeneous (Ulrich et al 1998;Homminga et al 2002;Vilayphiou et al 2010) or that tissue variability occurred at the microscale based on grey values from micro-CT scans (Jaecques et al 2004). More recently, various analytical (Porter 2004;Ji and Gao 2006;Hamed et al 2010;Martínez-Reina et al 2011) and computational (Ghanbari and Naghdabadi 2009;De Micheli and Witzel 2011;Yuan et al 2011) models have been proposed in order to fully predict macroscopic behaviour based on the nanostructural constituents.…”
Section: Introductionmentioning
confidence: 99%
“…Computational methods have been widely used to predict bone failure during disease and after prosthetic implantation, but for many years these methods assumed that the material behaviour was homogeneous (Ulrich et al 1998;Homminga et al 2002;Vilayphiou et al 2010) or that tissue variability occurred at the microscale based on grey values from micro-CT scans (Jaecques et al 2004). More recently, various analytical (Porter 2004;Ji and Gao 2006;Hamed et al 2010;Martínez-Reina et al 2011) and computational (Ghanbari and Naghdabadi 2009;De Micheli and Witzel 2011;Yuan et al 2011) models have been proposed in order to fully predict macroscopic behaviour based on the nanostructural constituents.…”
Section: Introductionmentioning
confidence: 99%
“…27 In fact for several years, µ-CT has been a standard tool for biomechanical evaluation and optimization in orthopedic surgery. Jaecques et al 28 even examined the postimplantation adaptation of bone tissue by µ-CT. The ability of µ-CT to visualize complex geometries precisely as tested in orthopedics is in line with results generated in this study.…”
Section: Discussionmentioning
confidence: 99%
“…In addition, this CT had an extremely low radiological dose, which was 1/100 of helical-CT 13) . The micro CT was developed as a highresolution imaging device and a precise FE modeling tool using the images 16) . However, it could not be adapted for human use because of its high radiological dose effect.…”
Section: Discussionmentioning
confidence: 99%