Indocyanine green angiography in inflammatory eye disease

Fluorescein and indocyanine green angiography in ocular toxoplasmosis

“…ICGA is currently the best tool available to evaluate the choroid [5,6]. Auer et al [2] showed marked choroidal involvement in toxoplasmic retinochoroiditis using ICGA, and found multiple hypofluorescent SDD in 75% of patients with acute toxoplasmic retinochoroiditis which disappeared after treatment.…”

Indocyanine green angiography findings in initial acute pretreatment Vogt-Koyanagi-Harada disease in Japanese patients

“…IA has been found to be particularly useful for early disease detection when no secondary spill-over infl ammation is present as yet. 19 The advantage of IA is that it allows localized choroidal infl ammation to be detected when it has not yet affected adjacent structures and become clinically apparent. It has to be kept in mind that in VKH disease the primary and main infl ammatory events take place and originate within the choroid, where the target of the autoimmune infl ammatory reaction is situated.…”

Suboptimal therapy controls clinically apparent disease but not subclinical progression of Vogt-Koyanagi-Harada disease

“…In contrast, ICGA is sensitive enough to detect small choroidal inflammatory foci and to provide information about the choriocapillaris circulation and inflammation of choroidal stromal vessels [9]. Thus, ICGA is currently the most appropriate method for investigating choroidal diseases, as it is sensitive enough to demonstrate minimal and, often, subclinical changes in the choroid [10][11][12]. Moreover, in cases of suspected VKH disease that do not have an acute onset or that are seen at a later stage, when suboptimal therapy has already been introduced, or that do not exhibit a complete set of signs, diagnosis of VKH becomes more difficult, and the diagnostic contribution of ICGA is especially useful [13][14][15][16][17].…”