1980
DOI: 10.1002/ange.19800920607
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Indolfarbstoffe aus Fruchtkörpern des SchleimpilzesArcyria denudata

Abstract: nen. da8 man uber systematische Fehler erst dann reden kann. wenn die Statistik in Ordnung ist. Experimental NMR Conference, Elsinore, Danemark 1977. [I011 Die sorgfaltige Wahl der Temperatur is1 kritisch. Bei zu langsamem Austausch is1 die Relaxation zu schnell, um den Magnetisierungstransfer noch anzuzeigen: bei zu hohen Ternperaturen wird die Sattigung durch schnelle Weitenvanderung auch in die anderen Positionen starker transferiert. 0 Verlag Chemie, GmbH, 0-6940 Weinheim, 1980

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Cited by 45 publications
(25 citation statements)
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“…13) (Steglich et al, 1980). The indole[2,3-a]carbazole alkaloid ring system is present in several biologically active molecules, such as the arcyriaflavins and related compounds (Steglich, 1989).…”
Section: Alkaloidsmentioning
confidence: 99%
“…13) (Steglich et al, 1980). The indole[2,3-a]carbazole alkaloid ring system is present in several biologically active molecules, such as the arcyriaflavins and related compounds (Steglich, 1989).…”
Section: Alkaloidsmentioning
confidence: 99%
“…For this purpose, N-methylbis(indolyl)maleimide 1 was chosen as the starting compound for the synthesis and prepared according to a procedure published by Steglich et al [18] 3,4-Bis[1-(carboxymethyl)-3-indolyl]-1H-pyrrole-2,5-dione (BIM-COOH) was prepared according to an adapted procedure described by Xie et al [19] (see Scheme 2) Methyl Scheme 2. Schematic procedure for the synthesis of BIM-COOH.…”
Section: Synthesis Of Bim-coohmentioning
confidence: 99%
“…5 More importantly, a fruitful strategy has been developed to design more selective inhibitors by disrupting the planarity of the indolocarbazole ring system. Among them, bisindolylmaleimides (BIMs) 6,7 derived from arcyriarubin A (3) 8,9 are successful examples, which are of interest because of their PKC inhibitory activity. Mono-N'-substituted BIMs such as compounds 4-6 ( Figure 1: for simplicity, the nitrogen in the maleimide ring is referred to as N, the other two nitrogens in indole rings are marked as N' and N'' respectively) represent a class of excellent PKC inhibitors.…”
Section: Introductionmentioning
confidence: 99%