Indoor air pollutants and respiratory outcomes among residents of an informal urban setting in Uganda: a cross-sectional study

Wafula, Solomon Tsebeni; Nalugya, Aisha; Mendoza, Hilbert; Kansiime, Winnifred K.; Ssekamatte, Tonny; Walekhwa, Abel Wilson; Mugambe, Richard K.; Walter, Florian; Ssempebwa, John C.; Musoke, David

doi:10.1101/2022.07.28.22278151

Cited by 4 publications

(4 citation statements)

References 40 publications

(47 reference statements)

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“…This is a secondary analysis of the main study which assessed the effect of indoor air quality on health outcomes. The sample size calculated was for the main study based on the prevalence of respiratory problems (main outcome)(p) at 19.4%, 80% power, 5% power and 15% non-response rate but this sample size still had acceptable power for this secondary objective [ 30 ]. A representative sample of households were selected from the three parishes in Bwaise.…”

Section: Methodsmentioning

confidence: 99%

Association between recent COVID-19 diagnosis, depression and anxiety symptoms among slum residents in Kampala, Uganda

et al. 2023

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Background Despite the known link between poor living conditions and mental health, there has been little research on the mental health of slum dwellers worldwide. Although the Coronavirus disease 2019 (COVID-19) pandemic has led to an increase in mental health issues, little focus has been given to the impact on slum dwellers. The study aimed to investigate the association between recent COVID-19 diagnosis and the risk of depression and anxiety symptoms among people living in an urban slum in Uganda. Methods A cross-sectional study was conducted among 284 adults (at least 18 years of age) in a slum settlement in Kampala, Uganda between April and May 2022. We assessed depression symptoms and anxiety using validated Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder assessment tool (GAD-7) questionnaires respectively. We collected data on sociodemographic characteristics, and self-reported recent COVID-19 diagnosis (in the previous 30 days). Using a modified Poisson regression, adjusted for age, sex, gender and household income, we separately provided prevalence ratios and 95% confidence intervals for the associations between recent COVID-19 diagnosis and depressive and anxiety symptoms. Results Overall, 33.8% and 13.4% of the participants met the depression and generalized anxiety screening criteria respectively and 11.3% were reportedly diagnosed with COVID-19 in the previous 30 days. People with recent COVID-19 diagnosis were more likely to be depressed (53.1%) than those with no recent diagnosis (31.4%) (p<0.001). Participants who were recently diagnosed with COVID-19 reported higher prevalence of anxiety (34.4%) compared to those with no recent diagnosis of COVID-19 (10.7%) (p = 0.014). After adjusting for confounding, recent diagnosis with COVID-19 was associated with depression (PR = 1.60, 95% CI 1.09–2.34) and anxiety (PR = 2.83, 95% CI 1.50–5.31). Conclusion This study suggests an increased risk of depressive symptoms and GAD in adults following a COVID-19 diagnosis. We recommend additional mental health support for recently diagnosed persons. The long-term of COVID-19 on mental health effects also need to be investigated.

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Section: Methodsmentioning

confidence: 99%

Association between recent COVID-19 diagnosis, depression and anxiety symptoms among slum residents in Kampala, Uganda

et al. 2023

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“…Previous FRESH AIR studies have shown significant exposure to HAP and high prevalence rates of COPD in rural communities in the Kyrgyz Republic and Uganda 151,152 . Additionally, in Uganda, HAP was independently associated with asthma and persistent (childhood) cough [153][154][155] . Females and children are mostly exposed to HAP 156,157 .…”

Section: Air Pollution Exposurementioning

confidence: 99%

The FRESHAIR4Life study: Global implementation research on non-communicable disease prevention targeting adolescents’ exposure to tobacco and air pollution in disadvantaged populations

Hoffman,

Versluis,

Chirila

et al. 2024

npj Prim. Care Respir. Med.

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The FRESHAIR4Life study aims to reduce the non-communicable disease (NCD) burden by implementing preventive interventions targeting adolescents’ exposure to tobacco use and air pollution (AP) worldwide. This paper presents the FRESHAIR4Life methodology and initial rapid review results. The rapid review, using various databases and PubMed, aimed to guide decision-making on risk factor focus, target areas, and populations. It showed variable NCD mortality rates related to tobacco use and AP across the participating countries, with tobacco as the main risk factor in the Kyrgyz Republic, Greece, and Romania, and AP prevailing in Pakistan and Uganda. Adolescent exposure levels, sources, and correlates varied. The study will continue with an in-depth situational analysis to guide the selection, adaptation, and integration of evidence-based interventions into the FRESHAIR4Life prevention package. This package will be implemented, evaluated, assessed for cost-effectiveness, and iteratively refined. The research places a strong emphasis on co-creation, capacity building, and comprehensive communication and dissemination.

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“…119 Additionally, some related studies have been done which could be points of comparison, including indoor air pollution levels in Vietnam 120 and Uganda. 121 Our study could be refined by using available data specific to Uganda and Vietnam. However, data for the same settings that covers the multiple dimensions in our analysis (e.g.…”

Section: Strengths and Limitationsmentioning

confidence: 99%

Do the Health Benefits of Boiling Drinking Water Outweigh the Negative Impacts of Increased Indoor Air Pollution Exposure?

Floess,

Ercumen,

Harris

et al. 2024

Preprint

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BackgroundBillions of the world’s poorest households are faced with the lack of access to both safe drinking water and clean cooking. One solution to microbiologically contaminated water is boiling, often promoted without acknowledging the additional risks incurred from indoor air degradation from using solid fuels.ObjectivesThis modeling study explores the tradeoff of increased air pollution from boiling drinking water under multiple contamination and fuel use scenarios typical of low-income settings.MethodsWe calculated the total change in disability-adjusted life years (DALYs) from indoor air pollution (IAP) and diarrhea from fecal contamination of drinking water for scenarios of different source water quality, boiling effectiveness, and stove type. We used Uganda and Vietnam, two countries with a high prevalence of water boiling and solid fuel use, as case studies.ResultsBoiling drinking water reduced the diarrhea disease burden by a mean of 1110 DALYs and 368 DALYs per 10,000 people for those under and over <5 years of age in Uganda, respectively, for high-risk water quality and the most efficient (lab-level) boiling scenario, with smaller reductions for less contaminated water and ineffective boiling. Similar results were found in Vietnam, though with fewer avoided DALYs in children under 5 due to different demographics. In both countries, for households with high baseline IAP from existing solid fuel use, adding water boiling to cooking on a given stove was associated with a limited increase in IAP DALYs due to the log-linear dose-response curves. Boiling, even at low effectiveness, was associated withnetDALY reductions for medium- and high-risk water, even with unclean stoves/fuels. Use of clean stoves coupled with effective boiling significantly reduced total DALYs.DiscussionBoiling water generally resulted in net decreases in DALYs. Future efforts should empirically measure health outcomes from IAP vs. diarrhea associated with boiling drinking water using field studies with different boiling methods and stove types.

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Indoor air pollutants and respiratory outcomes among residents of an informal urban setting in Uganda: a cross-sectional study

Cited by 4 publications

References 40 publications

Association between recent COVID-19 diagnosis, depression and anxiety symptoms among slum residents in Kampala, Uganda

Association between recent COVID-19 diagnosis, depression and anxiety symptoms among slum residents in Kampala, Uganda

The FRESHAIR4Life study: Global implementation research on non-communicable disease prevention targeting adolescents’ exposure to tobacco and air pollution in disadvantaged populations

Do the Health Benefits of Boiling Drinking Water Outweigh the Negative Impacts of Increased Indoor Air Pollution Exposure?

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