Indoor Environmental Risk Factors for Asthma and Respiratory Ill Health in Preschool Children of Coastal Orissa, India

Pati, Susmita; Parida, Suryakant

doi:10.1097/00001648-200509000-00335

Cited by 5 publications

(6 citation statements)

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“…This should not be surprising in that many of these studies serve as the foundation of our meta-analysis. However, in addition to the seven studies included in the meta-analysis, two additional studies, each reporting a positive association, could not be included, yet they provide further support for the observed quantitative results (Pati and Parida 2005;Tavernier et al 2006). Tavernier et al (2006) reported elevated but not statistically significant ORs for specific levels of formaldehyde exposure; unfortunately, the authors did not provide the actual, quantitative values associated with those levels.…”

Section: Discussionmentioning

confidence: 99%

“…Tavernier et al (2006) reported elevated but not statistically significant ORs for specific levels of formaldehyde exposure; unfortunately, the authors did not provide the actual, quantitative values associated with those levels. Similarly, Pati and Parida (2005) simply reported that, indoor exposure to formaldehyde . .…”

Section: Discussionmentioning

confidence: 99%

“…For the 10 articles included, we abstracted information regarding study design and setting, subject response/participation rates, definition of asthma (e.g., physician diagnosis), sample size, average (minimum and maximum) formaldehyde levels, average age of study subjects, and quantitative estimates (or raw data) for the association between formaldehyde exposure and asthma as well as whether such estimates were adjusted and, if so, for what measures (Table 1). Three of 10 studies did not contain actual formaldehyde measurements, and attempts to obtain this information from the study authors have been unsuccessful to date (Doi et al 2003;Pati and Parida 2005;Tavernier et al 2006).…”

Section: Methodsmentioning

confidence: 99%

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Formaldehyde exposure and asthma in children: a systematic review

McGwin

Lienert

Kennedy

2011

Ciênc. saúde coletiva

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Formaldehyde exposure and asthma in children: a systematic review Exposição ao formol e asma em crianças: uma revisão sistemáticaResumo Apesar de múltiplos estudos publicados sobre a associação entre exposição ao formol e asma infantil, uma relação consistente ainda não foi identificada. Nós relacionamos os resultados de revisão de estudos publicados a fim de fornecer uma imagem mais compreensível desta relação. Após pesquisa, foram identificados sete estudos que proviam resultados quantitativos sobre a associação entre a exposição ao formol e a asma infantil. Estudos foram heterogêneos em relação à definição de asma. Para cada estudo, uma razão de chances (RC) e 95% de intervalo de confiança (IC) para asma foram abstraídos de resultados publicados ou calculados baseados nos dados fornecidos. Foram usados modelos de efeitos fixos e aleatórios para calcular RC agrupados e IC de 95%; medidas de heterogeneidade também foram calculadas. Um modelo de efeitos fixos produziu um a RC de 1.03 (IC de 95%, 1.02-1.04), e o modelo de efeitos aleatórios produziu uma RC de 1.17 (IC de 95%, 1.01-1.36), ambos refletindo um aumento de 10 μg/m3 de exposição ao formol. As estatís-ticas de Q and I2 indicaram uma quantidade moderada de heterogeneidade. Resultados indicam uma associação positiva entre exposição ao formol e asma infantil. Devido à natureza de cruzamento de dados destes estudos por baixo desta meta-análise, um estudo de prospectiva epidemiológica mais aprofundada é necessário. Palavras-chave Asma, Crianças, Epidemiologia, Formol Abstract Despite multiple published studies regarding the association between formaldehyde exposure and childhood asthma, a consistent association has not been identified. Here we report the results of a systematic review of published literature in order to provide a more comprehensive picture of this relationship. After a literature search, we identified seven studies providing quantitative results regarding the association between formaldehyde exposure and asthma in children. Studies were heterogeneous with respect to the definition of asthma. For each study, an odds ratio (OR) and 95% confidence interval (CI) for asthma were abstracted from published results or calculated based on the data provided. We used fixed-and random-effects models to calculate pooled ORs and 95% CIs; measures of heterogeneity were also calculated. A fixed-effects model produced an OR of 1.03 (95% CI, 1.02-1.04), and random effects model produced an OR of 1.17 (95% CI, 1.01-1.36), both reflecting an increase of 10 μg/m3 of formaldehyde. Both the Q and I2 statistics indicated a moderate amount of heterogeneity. Results indicate a positive association between formaldehyde exposure and childhood asthma. Given the largely cross-sectional nature of the studies underlying this meta-analysis, further well-designed prospective epidemiologic studies are needed.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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Formaldehyde exposure and asthma in children: a systematic review

McGwin

Lienert

Kennedy

2011

Ciênc. saúde coletiva

View full text Add to dashboard Cite

show abstract

“…This should not be surprising in that many of these studies serve as the foundation of our meta-analysis. However, in addition to the seven studies included in the meta-analysis, two additional studies, each reporting a positive association, could not be included, yet they provide further support for the observed quantitative results ( Pati and Parida 2005 ; Tavernier et al 2006 ). Tavernier et al (2006) reported elevated but not statistically significant ORs for specific levels of formaldehyde exposure; unfortunately, the authors did not provide the actual, quantitative values associated with those levels.…”

Section: Discussionmentioning

confidence: 99%

“…For the 10 articles included, we abstracted information regarding study design and setting, subject response/participation rates, definition of asthma (e.g., physician diagnosis), sample size, average (minimum and maximum) formaldehyde levels, average age of study subjects, and quantitative estimates (or raw data) for the association between formaldehyde exposure and asthma as well as whether such estimates were adjusted and, if so, for what measures ( Table 1 ). Three of 10 studies did not contain actual formaldehyde measurements, and attempts to obtain this information from the study authors have been unsuccessful to date ( Doi et al 2003 ; Pati and Parida 2005 ; Tavernier et al 2006 ).…”

Section: Methodsmentioning

confidence: 99%

Formaldehyde Exposure and Asthma in Children: A Systematic Review

McGwin

Lienert

Kennedy

2010

Environ Health Perspect

240

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ObjectiveDespite multiple published studies regarding the association between formaldehyde exposure and childhood asthma, a consistent association has not been identified. Here we report the results of a systematic review of published literature in order to provide a more comprehensive picture of this relationship.Data sourcesAfter a comprehensive literature search, we identified seven peer-reviewed studies providing quantitative results regarding the association between formaldehyde exposure and asthma in children. Studies were heterogeneous with respect to the definition of asthma (e.g., self-report, physician diagnosis). Most of the studies were cross-sectional.Data extractionFor each study, an odds ratio (OR) and 95% confidence interval (CI) for asthma were either abstracted from published results or calculated based on the data provided. Characteristics regarding the study design and population were also abstracted.Data synthesisWe used fixed- and random-effects models to calculate pooled ORs and 95% CIs; measures of heterogeneity were also calculated. A fixed-effects model produced an OR of 1.03 (95% CI, 1.02–1.04), and random effects model produced an OR of 1.17 (95% CI, 1.01–1.36), both reflecting an increase of 10 μg/m3 of formaldehyde. Both the Q and I2 statistics indicated a moderate amount of heterogeneity.ConclusionsResults indicate a significant positive association between formaldehyde exposure and childhood asthma. Given the largely cross-sectional nature of the studies underlying this meta-analysis, further well-designed prospective epidemiologic studies are needed.

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Formaldehyde and Other Saturated Aldehydes

Leikauf¹

2020

Environmental Toxicants

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Indoor Environmental Risk Factors for Asthma and Respiratory Ill Health in Preschool Children of Coastal Orissa, India

Cited by 5 publications

References 0 publications

Formaldehyde exposure and asthma in children: a systematic review

Formaldehyde exposure and asthma in children: a systematic review

Formaldehyde Exposure and Asthma in Children: A Systematic Review

Formaldehyde and Other Saturated Aldehydes

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